RNF7 and UBE2F

Number of citations of the paper that reports this interaction (PubMedID 19250909)
87

Data Source:
BioGRID (pull down, pull down, pull down, pull down, x-ray crystallography)

		RNF7	UBE2F
Description		ring finger protein 7	ubiquitin conjugating enzyme E2 F (putative)
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cullin-RING Ubiquitin Ligase Complex Cul2-RING Ubiquitin Ligase Complex Cul3-RING Ubiquitin Ligase Complex Cul5-RING Ubiquitin Ligase Complex Cul7-RING Ubiquitin Ligase Complex Nuclear SCF Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex	Cytosol
	Molecular Function	Copper Ion Binding Protein Binding Zinc Ion Binding NEDD8 Transferase Activity Ubiquitin Protein Ligase Activity NEDD8 Ligase Activity Cullin Family Protein Binding	Protein Binding ATP Binding NEDD8 Transferase Activity Ubiquitin Conjugating Enzyme Activity NEDD8 Conjugating Enzyme Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Protein Neddylation Response To Redox State	Protein Ubiquitination Post-translational Protein Modification Protein Neddylation
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Hepatitis C induced liver fibrosis ( 22841784) Pelvic organ prolapse (moderate/severe) ( 26545240)	Lean body mass ( 28552196)
Interacting Genes		40 interacting genes: BTRC CASP7 CBFB CDC34 CHFR CSNK2A1 CSNK2B CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CYCS ELOB ELOC ERBIN GEM GHR GLMN IKBKG ITM2C MKRN3 MNAT1 NEDD4 NEDD4L PLA2G15 PMAIP1 SOCS3 TRIM46 TRIM8 UBE2C UBE2D1 UBE2D2 UBE2D4 UBE2F UBE2L3 UBE2M UBE2Q1 UBE2S	10 interacting genes: CUL1 CUL5 DCUN1D1 DCUN1D2 DCUN1D5 NAE1 RC3H1 RNF34 RNF7 UBA3
Entrez ID		9616	140739
HPRD ID		04840	14812
Ensembl ID		ENSG00000114125	ENSG00000184182
Uniprot IDs		Q9UBF6	Q969M7
PDB IDs		2ECL	2EDI 3FN1 4GBA
Enriched GO Terms of Interacting Partners?
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