APOBEC3B and MSL2

Number of citations of the paper that reports this interaction (PubMedID 28608964)
15

Data Source:
BioGRID (enzymatic study)

		APOBEC3B	MSL2
Description		apolipoprotein B mRNA editing enzyme catalytic subunit 3B	MSL complex subunit 2
Image
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm	Nucleoplasm MSL Complex
	Molecular Function	RNA Binding Cytidine Deaminase Activity Zinc Ion Binding Deoxycytidine Deaminase Activity	Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cytidine Deamination Negative Regulation Of Transposition Cytidine To Uridine Editing Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Defense Response To Virus DNA Cytosine Deamination DNA Demethylation	Protein Ubiquitination Histone H4-K16 Acetylation
Pathways		mRNA Editing: C to U Conversion Formation of the Editosome	HATs acetylate histones
Drugs
Diseases
GWAS		Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Breast cancer ( 29059683) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)	Alanine transaminase levels ( 29403010) Autism spectrum disorder or schizophrenia ( 28540026) Blood urea nitrogen levels ( 31152163) C-reactive protein levels ( 30388399) Coronary artery disease ( 29212778) Estimated glomerular filtration rate ( 31152163) Fibrinogen ( 23969696) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Height ( 31217584) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Schizophrenia ( 28991256 25056061 29483656) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		1 interacting genes: MSL2	13 interacting genes: APOBEC3B H2AC18 H2AC20 H2BC21 H3C14 H4C1 PAF1 TP53 TRIM8 UBE2D3 YWHAE YWHAG YWHAZ
Entrez ID		9582	55167
HPRD ID		06169	08550
Ensembl ID		ENSG00000179750	ENSG00000174579
Uniprot IDs		Q9UH17	Q9HCI7
PDB IDs		2NBQ 5CQD 5CQH 5CQI 5CQK 5SXG 5SXH 5TD5 5TKM	4B7Y 4B86
Enriched GO Terms of Interacting Partners?
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