SCARB1 and CASP10

SCARB1

CASP10

Description scavenger receptor class B member 1 caspase 10
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Coronary artery disease ( 29212778)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • HDL cholesterol ( 24097068 30275531 25961943 20686565)
  • HDL cholesterol levels ( 28334899 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • High density lipoprotein cholesterol levels ( 29403010 31217584)
  • Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643)
  • Lipoprotein-associated phospholipase A2 activity and mass ( 23118302 20442857)
  • Lung function (FEV1) ( 30061609)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Metabolite levels (lipoprotein measures) ( 27005778)
  • Renal cell carcinoma ( 21131975)
  • Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576)
  • Total bilirubin levels ( 29403010)
  • Total cholesterol levels ( 29403010)
  • Triglycerides ( 30275531)
  • Vitamin E levels ( 21729881)
Interacting Genes 16 interacting genes: APOA1 APOA2 APOE CASP10 DENR GGA1 GTF2H3 KRTAP10-9 KRTAP5-9 PDZK1 PEX5 POLE PRL PXN SNAP23 SRSF9 32 interacting genes: BFAR BID CASP1 CASP14 CASP2 CASP3 CASP4 CASP6 CASP7 CASP8 CASP8AP2 CASP9 CCAR1 CFLAR DEDD DEDD2 DSP ECE2 FADD NFKBIL1 NPTX1 OIP5 PHF20L1 POLR2A PRDX6 RB1 RIOK3 RYBP SCARB1 TNFRSF1A TRAF1 XIAP
Entrez ID 949 843
HPRD ID 03024 03458
Ensembl ID ENSG00000073060 ENSG00000003400
Uniprot IDs A0A024RBS4 Q8WTV0 A0A0S2Z3G5 A0A0S2Z3Z5 Q92851
PDB IDs
Enriched GO Terms of Interacting Partners?
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