HOMER2 and UBXN1

Number of citations of the paper that reports this interaction (PubMedID 15944415)
10

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		HOMER2	UBXN1
Description		homer scaffold protein 2	UBX domain protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Cell Junction Dendrite Stereocilium Tip Neuron Projection Neuronal Cell Body Apical Part Of Cell Glutamatergic Synapse	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Dendrite VCP-NPL4-UFD1 AAA ATPase Complex Neuronal Cell Body
	Molecular Function	Actin Binding Protein Binding Protein Domain Specific Binding GKAP/Homer Scaffold Activity G Protein-coupled Glutamate Receptor Binding Identical Protein Binding Protein-containing Complex Binding	Protein Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Protein Ligase Binding K48-linked Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding ATPase Binding K6-linked Polyubiquitin Modification-dependent Protein Binding Proteasome Regulatory Particle Binding
	Biological Process	G Protein-coupled Glutamate Receptor Signaling Pathway Sensory Perception Of Sound Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Signal Transduction Negative Regulation Of Interleukin-2 Production Calcium-mediated Signaling Using Intracellular Calcium Source Behavioral Response To Cocaine Chemical Homeostasis Within A Tissue Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Store-operated Calcium Entry	Protein Folding Viral Process Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein K48-linked Deubiquitination Negative Regulation Of ERAD Pathway Negative Regulation Of Ubiquitin-specific Protease Activity
Pathways		Neurexins and neuroligins Neurexins and neuroligins	N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Drugs
Diseases
GWAS		Tourette syndrome ( 30818990)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		12 interacting genes: AGAP2 APP DBN1 GRM1 ITPR1 KPNA2 LZTS2 PJA1 RYR1 SMURF1 UBXN1 VKORC1	15 interacting genes: ACVR1 BARD1 BMPR1B BRCA1 FAM189A2 HOMER2 PLA2G4A PLAA SMAD1 SMURF1 TGFBR1 TRIM39 UBC UBE2I UBQLN1
Entrez ID		9455	51035
HPRD ID		07269	11266
Ensembl ID		ENSG00000103942	ENSG00000162191
Uniprot IDs		Q9NSB8	A0A024R539 A0A024R598 A0A087WTZ5 Q04323
PDB IDs
Enriched GO Terms of Interacting Partners?
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