ECEL1 and USP19

Number of citations of the paper that reports this interaction (PubMedID 23500468)
2

Data Source:
BioGRID (two hybrid)

		ECEL1	USP19
Description		endothelin converting enzyme like 1	ubiquitin specific peptidase 19
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane	Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane
	Molecular Function	Metalloendopeptidase Activity Metallopeptidase Activity Metal Ion Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Ubiquitin Protein Ligase Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Metal Ion Binding Hsp90 Protein Binding Lys48-specific Deubiquitinase Activity
	Biological Process	Respiratory System Process Proteolysis Neuropeptide Signaling Pathway	Protein Deubiquitination Ubiquitin-dependent ERAD Pathway Regulation Of Protein Stability Response To Endoplasmic Reticulum Stress Negative Regulation Of Skeletal Muscle Tissue Development Protein Stabilization Protein K48-linked Deubiquitination Positive Regulation Of Cell Cycle Process Regulation Of Cellular Response To Hypoxia Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of ERAD Pathway
Pathways			Ub-specific processing proteases
Drugs
Diseases
GWAS			Blood protein levels ( 28240269) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		2 interacting genes: BRD2 USP19	13 interacting genes: BIRC3 CKAP5 ECEL1 FLNA HIF1A HNRNPAB HSP90AA1 LAMTOR4 RNF2 SIAH1 SIAH2 SNRNP200 UBC
Entrez ID		9427	10869
HPRD ID		07066	18278
Ensembl ID		ENSG00000171551	ENSG00000172046
Uniprot IDs		O95672	O94966
PDB IDs			1WH0 4X3G
Enriched GO Terms of Interacting Partners?
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