DDX23 and PCM1

Number of citations of the paper that reports this interaction (PubMedID 30217970)
1

Data Source:
BioGRID (two hybrid)

		DDX23	PCM1
Description		DEAD-box helicase 23	pericentriolar material 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U5 SnRNP Nucleolus U4/U6 X U5 Tri-snRNP Complex Extracellular Exosome Catalytic Step 2 Spliceosome	Pericentriolar Material Cytoplasm Centrosome Centriole Cytosol Membrane Nuclear Membrane Protein-containing Complex Centriolar Satellite Ciliary Transition Zone Ciliary Basal Body Apical Part Of Cell Non-motile Cilium
	Molecular Function	RNA Binding Helicase Activity Protein Binding ATP Binding	Protein Binding Identical Protein Binding
	Biological Process	Cis Assembly Of Pre-catalytic Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing	G2/M Transition Of Mitotic Cell Cycle Neuron Migration Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Interkinetic Nuclear Migration Cytoplasmic Microtubule Organization Microtubule Anchoring Microtubule Anchoring At Centrosome Social Behavior Intraciliary Transport Involved In Cilium Assembly Negative Regulation Of Neurogenesis Cilium Assembly Protein Localization To Centrosome Positive Regulation Of Intracellular Protein Transport Neuronal Stem Cell Population Maintenance Ciliary Basal Body-plasma Membrane Docking Non-motile Cilium Assembly
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Atrial fibrillation ( 28416818) Economic and political preferences ( 22566634) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Waist-hip ratio ( 30108283) Weight ( 28552196)
Interacting Genes		5 interacting genes: ERG PCM1 TERF1 TERF2IP WBP4	39 interacting genes: ABI1 ABI2 AKAP9 BBS4 CASK CCDC172 CCHCR1 CDC42 CEP72 DDIT3 DDX23 DYNLL1 E2F4 ECPAS EPS8 EXOC8 FXR2 GABARAP GOLGA2 HAP1 ING5 KLC1 KLC4 KRT15 KRT19 KRT24 NDC80 NECAB2 PCNT PRC1 PRKCI RBM5 RINT1 RPA2 TFIP11 TTC8 WASHC3 YWHAE YWHAQ
Entrez ID		9416	5108
HPRD ID		09908	02624
Ensembl ID		ENSG00000174243	ENSG00000078674
Uniprot IDs		A0A024R0Z3 B3KY11 Q9BUQ8	A2RUU9 B9EIS5 Q15154
PDB IDs		3JCR 4NHO 6AH0 6QW6 6QX9	6HYL 6HYM
Enriched GO Terms of Interacting Partners?
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