COPS2 and NIF3L1

Number of citations of the paper that reports this interaction (PubMedID 12522100)
10

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		COPS2	NIF3L1
Description		COP9 signalosome subunit 2	NGG1 interacting factor 3 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol COP9 Signalosome	Nucleus Cytoplasm Mitochondrion
	Molecular Function	Transcription Corepressor Activity Protein Binding	Protein Binding Transcription Factor Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition Inner Cell Mass Cell Proliferation Transcription-coupled Nucleotide-excision Repair Transcription By RNA Polymerase II Protein Phosphorylation Signal Transduction Neuron Differentiation Skeletal Muscle Cell Differentiation Post-translational Protein Modification Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription	Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
Drugs
Diseases
GWAS		Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung function (FEV1/FVC) ( 30804560) Peak expiratory flow ( 30804560)	Triptolide cytotoxicity ( 26121980)
Interacting Genes		35 interacting genes: COPS3 COPS4 COPS5 COPS6 COPS7A COPS8 CSNK2A1 CUL1 CUL5 DDB1 EP300 GFER GPS1 H3C1 H4C1 ING1 ING2 IP6K1 IRF8 MAP3K10 MAPK8 NCOR1 NIF3L1 NR0B1 NR2F1 PRKD1 RARA RXRA SENP8 SIN3A SIN3B THRA THRB TP53 VDR	67 interacting genes: AP5B1 APIP ARPIN BEND7 CCDC102B CCDC85B CDKN2B CDKN2C COIL COPS2 CUTC CYRIB DCDC2 DCTD DCTPP1 DHPS DMC1 DMRTB1 DUSP23 DYNLT3 EIF5A2 ENOX1 EPHB6 FXR2 GNMT GRB2 KCTD17 KRT15 KXD1 LAMTOR3 LMO2 MAGEA11 MAPRE2 MLXIPL NATD1 NME1 NOL3 NUDT14 NUDT21 ORC5 PAICS PCBD1 PNMA1 PRTFDC1 RABAC1 RAD54B RPIA S100A1 SAT1 SNF8 SSX2IP STAT3 STK16 SULT1A2 SULT1A3 SYT17 THOC7 TIFA TRAF2 TRIM21 TRIM27 TRIP13 TSC22D4 VIM YES1 YWHAQ ZBED1
Entrez ID		9318	60491
HPRD ID		05146	10424
Ensembl ID		ENSG00000166200	ENSG00000196290
Uniprot IDs		P61201 Q59EL2	A0A024R3V5 A0A024R3V7 Q9GZT8
PDB IDs		4D10 4D18 4WSN 6A73 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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