IMP4 and ZBTB7B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		IMP4	ZBTB7B
Description		IMP U3 small nucleolar ribonucleoprotein 4	zinc finger and BTB domain containing 7B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Nucleolus Preribosome Small-subunit Processome Mpp10 Complex	Nucleus Nucleoplasm
	Molecular Function	Protein Binding SnoRNA Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Metal Ion Binding
	Biological Process	RRNA Processing	Negative Regulation Of Transcription By RNA Polymerase II NK T Cell Differentiation Transcription By RNA Polymerase II Ectoderm Development Lactation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Histone Deacetylation Response To Insulin Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Negative Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of NK T Cell Proliferation Regulation Of Transcription Involved In Cell Fate Commitment Interleukin-17 Secretion Positive Regulation Of Brown Fat Cell Differentiation Positive Regulation Of Cold-induced Thermogenesis Adaptive Thermogenesis Negative Regulation Of T-helper 17 Cell Differentiation Positive Regulation Of SREBP Signaling Pathway
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Basal cell carcinoma ( 31174203) Bipolar disorder ( 31043756) Birth weight ( 27680694) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29273807) Keratinocyte cancer (MTAG) ( 31174203) Multiple sclerosis ( 31604244) Prostate cancer ( 23535732) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		4 interacting genes: APP MPHOSPH10 S100B ZBTB7B	19 interacting genes: BCL6 CRBN EP300 GRAP2 GRB2 IMP4 KPNA2 MORF4L2 NCK2 NDN PIN1 RELA RPL9 SH3KBP1 SH3YL1 SORBS3 SYTL4 ZBTB5 ZNF277
Entrez ID		92856	51043
HPRD ID		10002	09625
Ensembl ID		ENSG00000136718	ENSG00000160685
Uniprot IDs		E7ENR5 Q96G21	O15156
PDB IDs
Enriched GO Terms of Interacting Partners?
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