TSPOAP1 and ARNT2

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		TSPOAP1	ARNT2
Description		TSPO associated protein 1	aryl hydrocarbon receptor nuclear translocator 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Calyx Of Held Glutamatergic Synapse	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm
	Molecular Function	Protein Binding Benzodiazepine Receptor Binding Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Aryl Hydrocarbon Receptor Binding Protein-containing Complex Binding Protein Heterodimerization Activity
	Biological Process	C21-steroid Hormone Biosynthetic Process Neurotransmitter Secretion Neuromuscular Synaptic Transmission Biological_process Glutamate Secretion Regulation Of Presynaptic Cytosolic Calcium Ion Concentration	Response To Hypoxia In Utero Embryonic Development Regulation Of Transcription, DNA-templated Xenobiotic Metabolic Process Central Nervous System Development Brain Development Positive Regulation Of Cell Proliferation Response To Estradiol Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Pregnenolone biosynthesis Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle	PPARA activates gene expression Phase I - Functionalization of compounds Endogenous sterols Xenobiotics Aryl hydrocarbon receptor signalling
Drugs
Diseases
GWAS			Atrial fibrillation ( 30061737 29892015) Attention deficit hyperactivity disorder ( 29325848) Bipolar disorder ( 20351715) Body mass index ( 26426971) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		19 interacting genes: ANKRD11 ARNT2 BEND5 CACNA1A CADPS2 CEP76 DISC1 DLGAP2 DLX2 GPRASP2 KHDRBS1 KIF1A MVP NDE1 RAPGEF4 REL TCF4 TSC22D4 TSPO	62 interacting genes: ADAMTSL4 AHR APP ARNT CALCOCO2 CCDC33 CDR2 CEP57L1 CEP63 CTBP1 DGCR6 DTX2 DYDC1 EPAS1 GOLGA2 HIF1A IKZF3 KIFC3 LZTS2 MAGEA4 MAGED1 MEIS2 MEOX2 MIPOL1 MTDH MTUS2 NCOA3 NDE1 NPAS2 NPAS3 NPAS4 PDE4DIP PLSCR1 RBCK1 REL RFX6 RIMBP3 RINT1 SH3GL2 SIM1 SIM2 SORBS3 SPAG5 SSBP3 SSX2IP SYCE1 TACC3 TADA2A TAX1BP3 TFIP11 TRAF1 TRAF2 TRIM23 TRIM27 TRIM37 TRIM42 TRIP6 TSPOAP1 USHBP1 USP7 VPS52 ZNF341
Entrez ID		9256	9915
HPRD ID		09832	06915
Ensembl ID		ENSG00000005379	ENSG00000172379
Uniprot IDs		A7E2C5 B2RUT8 B7ZVZ7 O95153 X5DQQ3	Q7Z3A3 Q86TN1 Q9HBZ2 X5DQN9
PDB IDs
Enriched GO Terms of Interacting Partners?
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