NEK9 and JDP2

		NEK9	JDP2
Description		NIMA related kinase 9	Jun dimerization protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Centrosome Cytosol	Nuclear Chromatin Nucleus
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Chromatin Binding Transcription Corepressor Activity Protein Binding Protein-containing Complex Binding
	Biological Process	Protein Phosphorylation Mitotic Nuclear Envelope Disassembly Cell Division	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Deacetylation Negative Regulation Of Fat Cell Differentiation
Pathways		Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation
Drugs			Pseudoephedrine
Diseases
GWAS		Coronary artery disease ( 29212778) Feeling fed-up ( 29500382)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Basal cell carcinoma ( 31174203) Keratinocyte cancer (MTAG) ( 31174203) Multiple sclerosis ( 24076602) Obesity-related traits ( 23251661) Periodontal microbiota ( 22699663)
Interacting Genes		18 interacting genes: BICD2 CSN2 GZMB IFT43 JDP2 LIN52 MALL MBP MPP5 NEK6 NEK7 NEK8 RAN RARG RPS6KL1 SSRP1 SUPT16H WDR33	19 interacting genes: ATF2 CREBBP EP300 GTF2H1 HDAC1 HDAC4 HDAC5 HDAC6 IRF2BP1 JUN JUNB JUND KAT2B MAPK14 MAPK8 MAPK9 NEK9 PGR SNW1
Entrez ID		91754	122953
HPRD ID		11386	16360
Ensembl ID		ENSG00000119638	ENSG00000140044
Uniprot IDs		Q6PKF2 Q8TD19	A0A024R6D7 Q8WYK2
PDB IDs		3ZKE 3ZKF
Enriched GO Terms of Interacting Partners?
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