CBFA2T2 and TCP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CBFA2T2	TCP1
Description		CBFA2/RUNX1 partner transcriptional co-repressor 2	t-complex 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Pericentriolar Material Acrosomal Vesicle Zona Pellucida Receptor Complex Nuclear Heterochromatin Golgi Apparatus Centrosome Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Exosome
	Molecular Function	DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding	RNA Binding Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Unfolded Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Negative Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Intestinal Epithelial Cell Differentiation	Protein Folding Tubulin Complex Assembly Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Interleukin-12-mediated Signaling Pathway Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm Protein Stabilization Positive Regulation Of Telomerase Activity ScaRNA Localization To Cajal Body Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body Regulation Of Macrophage Apoptotic Process
Pathways			Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS		Height ( 28552196)
Interacting Genes		22 interacting genes: APP ATN1 ATXN1L CBFA2T3 CBFB FBXL19 GTF2E1 ID3 LBP MDFI NCOR1 NCOR2 NEUROG1 NOTCH3 NTAQ1 PDP1 RERE RUNX1 SIN3A TAL2 TCP1 ZNF652	11 interacting genes: CBFA2T2 CCT5 CCT7 CDC20 FANCA PDCL SH3BP4 TUBA4A TUBA8 VRK2 YWHAQ
Entrez ID		9139	6950
HPRD ID		04721	01748
Ensembl ID		ENSG00000078699	ENSG00000120438
Uniprot IDs		O43439	E7EQR6 P17987
PDB IDs			6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8
Enriched GO Terms of Interacting Partners?
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