RABEP1 and GGA3

Number of citations of the paper that reports this interaction (PubMedID 12505986)
55

Data Source:
HPRD (in vivo, two hybrid)

		RABEP1	GGA3
Description		rabaptin, RAB GTPase binding effector protein 1	golgi associated, gamma adaptin ear containing, ARF binding protein 3
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GO Annotations	Cellular Component	Endosome Early Endosome Endocytic Vesicle Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle Recycling Endosome	Golgi Apparatus Trans-Golgi Network Endosome Membrane Early Endosome Membrane Recycling Endosome Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Growth Factor Activity Protein Domain Specific Binding Protein Homodimerization Activity	Protein Binding ADP-ribosylation Factor Binding Ubiquitin Binding
	Biological Process	Golgi To Plasma Membrane Transport Endocytosis Apoptotic Process Signal Transduction Protein Transport Vesicle-mediated Transport Positive Regulation Of GTPase Activity Membrane Fusion Protein Localization To Ciliary Membrane	Intracellular Protein Transport Regulation Of Protein Stability Protein Destabilization Endocytic Recycling Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport Cellular Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Protein Localization To Lysosome Negative Regulation Of Amyloid-beta Formation
Pathways		TBC/RABGAPs	TBC/RABGAPs MET receptor recycling Amyloid fiber formation
Drugs
Diseases
GWAS		Body mass index ( 28892062 25673413) Red blood cell density in sickle cell anemia ( 28552477) White blood cell count ( 27863252)
Interacting Genes		24 interacting genes: AP1G1 AP1G2 ATXN7 CASP3 CCND1 GAP43 GGA1 GGA2 GGA3 HUNK ITSN1 ITSN2 RAB1A RAB33B RAB4A RAB5A RABGEF1 RGS17 SMURF1 SRPK2 TRIM26 TSC2 UBC YWHAG	29 interacting genes: ADRA2A ADRA2B AFTPH AP1S2 ARAP3 ARF1 ARF3 CDKN2A CLINT1 CLTC CYTH2 EGFR GGA1 GGA2 IGF2R LRP10 M6PR PACS1 RABEP1 RNF11 RPS27A STAB1 SYNRG TBC1D3 TOLLIP TSG101 UBC VPS11 VPS18
Entrez ID		9135	23163
HPRD ID		04684	10443
Ensembl ID		ENSG00000029725	ENSG00000125447
Uniprot IDs		B4DMM4 Q15276	A8K6M0 B7Z456 Q9NZ52
PDB IDs		1P4U 1TU3 1X79 4N3Y 4N3Z 4Q9U	1JPL 1JUQ 1LF8 1P4U 1WR6 1YD8
Enriched GO Terms of Interacting Partners?
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