AIFM1 and STC2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		AIFM1	STC2
Description		apoptosis inducing factor mitochondria associated 1	stanniocalcin 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytosol Perinuclear Region Of Cytoplasm	Extracellular Space Cell Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Protein Binding NAD(P)H Oxidase Activity Oxidoreductase Activity, Acting On NAD(P)H Protein Dimerization Activity FAD Binding	Hormone Activity Enzyme Binding Heme Binding Protein Homodimerization Activity
	Biological Process	Response To Ischemia Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Chromosome Condensation Mitochondrial Respiratory Chain Complex Assembly Positive Regulation Of Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Protein Import Into Mitochondrial Intermembrane Space Neuron Apoptotic Process Oxidation-reduction Process Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hydrogen Peroxide Cellular Response To Estradiol Stimulus Cellular Response To Nitric Oxide Cellular Response To Oxygen-glucose Deprivation Response To L-glutamate Regulation Of Apoptotic DNA Fragmentation Cellular Response To Aldosterone	Cellular Calcium Ion Homeostasis Response To Oxidative Stress Embryo Implantation Negative Regulation Of Gene Expression Endoplasmic Reticulum Unfolded Protein Response Response To Vitamin D Negative Regulation Of Multicellular Organism Growth Response To Peptide Hormone Post-translational Protein Modification Cellular Protein Metabolic Process Decidualization Regulation Of Hormone Biosynthetic Process Cellular Response To Hypoxia Regulation Of Store-operated Calcium Entry
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		Flavin adenine dinucleotide MCC
Diseases		Combined oxidative phosphorylation deficiency (COXPD)
GWAS		Bipolar disorder ( 31043756)	Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Atrial fibrillation ( 29892015) Birth weight ( 31043758) Height ( 25429064 31562340) Immunoglobulin A vasculitis ( 28698626) Prostate cancer ( 23535732) Urate levels in overweight individuals ( 25811787)
Interacting Genes		12 interacting genes: CASP3 DCAF7 EIF3G HSPA1A HSPA1B MLH1 NOA1 SETDB1 STC2 TSC22D4 WWC1 XIAP	20 interacting genes: ADAM11 AIFM1 ARHGEF40 ARRB2 CARHSP1 CELF6 CPN1 EIF2B3 ELOB ERGIC1 FAF2 FGFR4 HK3 PEBP1 PLA2G5 POLR2C POLR3F PPP1R8 PTN RNF44
Entrez ID		9131	8614
HPRD ID		02161	04717
Ensembl ID		ENSG00000156709	ENSG00000113739
Uniprot IDs		E9PMA0 O95831	O76061 Q6FHC9
PDB IDs		1M6I 4BUR 4BV6 4FDC 4LII 5FMH 5FS6 5FS7 5FS8 5FS9 5KVH 5KVI
Enriched GO Terms of Interacting Partners?
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