CNOT9 and GIGYF1

Number of citations of the paper that reports this interaction (PubMedID 20878056)
6

Data Source:
BioGRID (affinity chromatography technology, pull down)

		CNOT9	GIGYF1
Description		CCR4-NOT transcription complex subunit 9	GRB10 interacting GYF protein 1
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GO Annotations	Cellular Component	P-body Nucleus Cytosol Membrane CCR4-NOT Complex CCR4-NOT Core Complex Protein-containing Complex	Protein-containing Complex
	Molecular Function	Epidermal Growth Factor Receptor Binding Protein Binding Kinase Binding Protein Domain Specific Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Sex Differentiation Negative Regulation Of Translation Cytokine-mediated Signaling Pathway Gene Silencing By RNA Positive Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Nuclear Receptor Transcription Coactivator Activity	Biological_process Insulin-like Growth Factor Receptor Signaling Pathway
Pathways		Deadenylation of mRNA Activation of anterior HOX genes in hindbrain development during early embryogenesis TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS			LDL cholesterol ( 30275531) Pursuit maintenance gain ( 29064472) Pursuit maintenance gain in psychotic disorders ( 29064472) Resting heart rate ( 27798624)
Interacting Genes		8 interacting genes: AKT1 CNOT1 CNOT4 EGFR GIGYF1 GIGYF2 GRB10 MYB	6 interacting genes: ATN1 CNOT9 EIF4E2 GRB10 GRB14 GRB7
Entrez ID		9125	64599
HPRD ID		08828	10145
Ensembl ID		ENSG00000144580	ENSG00000146830
Uniprot IDs		D5MQE1 Q92600	O75420
PDB IDs		2FV2 4CRU 4CRV 4CT6 4CT7 5LSW 5ONA 5ONB 6HOM 6HON	5NVK
Enriched GO Terms of Interacting Partners?
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