TRIM41 and DEPTOR

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		TRIM41	DEPTOR
Description		tripartite motif containing 41	DEP domain containing MTOR interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Nuclear Body	Intracellular
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding	Protein Binding
	Biological Process	Protein Ubiquitination Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide	Negative Regulation Of Protein Kinase Activity Negative Regulation Of TOR Signaling Intracellular Signal Transduction Negative Regulation Of Cell Size Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Choroid plexus volume ( 31530798) Depressive and manic episodes in bipolar disorder ( 26297903) Depressive episodes in bipolar disorder ( 26297903) Estimated glomerular filtration rate ( 31152163) Heel bone mineral density ( 30598549)
Interacting Genes		62 interacting genes: AEN AKTIP APP BRAP CEP44 CHD2 CSNK2A2 DEPTOR EHHADH FAM124A FRA10AC1 GPATCH2L IKBKG KIFC3 KRTAP10-9 MAGEH1 MEOX2 MORF4L1 MPP3 NCK2 NEDD4L NOD2 PHC2 PHF7 PRKCA PRKCB PRPF31 PUS7L RNPS1 SORBS3 SRPK2 TLE5 TOP3B TRAIP TRIM17 TRIM26 TRIM4 TRIM52 UBE2D2 UBE2I ZBTB24 ZBTB38 ZBTB48 ZBTB8A ZFP2 ZFP64 ZNF138 ZNF24 ZNF250 ZNF26 ZNF263 ZNF264 ZNF266 ZNF329 ZNF417 ZNF473 ZNF490 ZNF564 ZNF587 ZNF670 ZSCAN21 ZSCAN26	12 interacting genes: APP BTRC CCDC110 CHKA CUL5 FBXO25 LNX1 PSME3 RPS6KA1 RPS6KB1 TRAF1 TRIM41
Entrez ID		90933	64798
HPRD ID		15558	13137
Ensembl ID		ENSG00000146063	ENSG00000155792
Uniprot IDs		Q8WV44	Q8TB45
PDB IDs		2EGM
Enriched GO Terms of Interacting Partners?
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