SYT7 and STX2

Number of citations of the paper that reports this interaction (PubMedID 7791877)
155

Data Source:
HPRD (in vitro)

		SYT7	STX2
Description		synaptotagmin 7	syntaxin 2
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Peroxisome Peroxisomal Membrane Cytosol Plasma Membrane Synaptic Vesicle Cell Junction Dendrite Phagocytic Vesicle Membrane Synaptic Vesicle Membrane Dense Core Granule Early Phagosome Neuronal Cell Body Axon Terminus Extracellular Exosome Exocytic Vesicle Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Presynaptic Membrane	Extracellular Space Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Protein-containing Complex Presynaptic Membrane Intracellular Membrane-bounded Organelle Presynaptic Active Zone Membrane
	Molecular Function	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calmodulin Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Syntaxin Binding Clathrin Binding	SNARE Binding Structural Molecule Activity SNAP Receptor Activity Protein Binding Calcium-dependent Protein Binding
	Biological Process	Plasma Membrane Repair Phagocytosis Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium Ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Synaptic Vesicle Recycling Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Bone Remodeling Calcium Ion-regulated Exocytosis Of Neurotransmitter Regulation Of Phagocytosis Regulation Of Insulin Secretion Regulation Of Glucagon Secretion Cellular Response To Calcium Ion Vesicle-mediated Cholesterol Transport Phagosome-lysosome Fusion Calcium-dependent Activation Of Synaptic Vesicle Fusion Regulation Of Synaptic Vesicle Endocytosis Short-term Synaptic Potentiation Calcium Ion Regulated Lysosome Exocytosis	Intracellular Protein Transport Exocytosis Vesicle Fusion Signal Transduction Acrosome Reaction Ectoderm Development Animal Organ Morphogenesis Cell Differentiation Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cellular Response To Oxidative Stress Vesicle Docking Cornified Envelope Assembly
Pathways		Neurexins and neuroligins
Drugs
Diseases
GWAS		Intelligence (MTAG) ( 29326435) Mean arterial pressure ( 26390057) Metabolite levels ( 23823483) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311)	Initial pursuit acceleration in psychotic disorders ( 29064472) Metabolite levels ( 23823483) Plasma plasminogen activator levels ( 24578379) vWF levels ( 30586737)
Interacting Genes		8 interacting genes: AP2A1 NRXN1 SIAH1 STX1A STX2 STX3 STX4 SYNCRIP	10 interacting genes: CPLX2 SNAP25 STXBP1 STXBP2 SYT1 SYT4 SYT7 UNC13B VAMP3 VAPB
Entrez ID		9066	2054
HPRD ID		11965	11816
Ensembl ID		ENSG00000011347	ENSG00000111450
Uniprot IDs		O43581	P32856
PDB IDs		2D8K
Enriched GO Terms of Interacting Partners?
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