CCDC120 and SFI1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCDC120	SFI1
Description		coiled-coil domain containing 120	SFI1 centrin binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Centriole Growth Cone Centriolar Subdistal Appendage	Centrosome Centriole Cytosol
	Molecular Function	Protein Binding	Protein Binding Phosphatase Binding
	Biological Process	Multicellular Organism Development Protein Localization Microtubule Anchoring At Centrosome	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Phosphatase Activity Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS			Age-related hearing impairment ( 24939585) Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Metabolite levels ( 23823483) Type 2 diabetes ( 31118516)
Interacting Genes		19 interacting genes: BRCA1 CCDC102B CCDC57 CCDC85B CEP170P1 CYTH2 DAZAP2 EFHC2 KRT15 KRT31 KRT40 LMNA MDFI MID2 SFI1 SMARCB1 TRAF1 USHBP1 ZDHHC17	14 interacting genes: CCDC120 CCDC57 CETN2 CRX FAM131C GCSH GOLGA2 KRT19 LPXN MAD2L2 MDFI RADIL RBPMS SERTAD1
Entrez ID		90060	9814
HPRD ID		06595	11550
Ensembl ID		ENSG00000147144	ENSG00000198089
Uniprot IDs		Q96HB5	A8K8P3
PDB IDs			2K2I
Enriched GO Terms of Interacting Partners?
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