NAV2 and ING5

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		NAV2	ING5
Description		neuron navigator 2	inhibitor of growth family member 5
Image
GO Annotations	Cellular Component	Interstitial Matrix Nucleoplasm	Nucleus Nucleoplasm MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	DNA Helicase Activity Protein Binding ATP Binding Heparin Binding	Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Nervous System Development Sensory Perception Of Sound Sensory Perception Of Smell Locomotory Behavior Optic Nerve Development Glossopharyngeal Nerve Development Vagus Nerve Development Neurogenesis DNA Duplex Unwinding	DNA Replication Protein Acetylation Negative Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Apoptotic Signaling Pathway
Pathways			HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Atrial fibrillation ( 30061737 29892015) Bone mineral density x blood lead interaction in current smokers (2df test) ( 29518117) Coronary artery aneurysm in Kawasaki disease ( 27171184) General cognitive ability ( 29844566) Hepatitis ( 25705159) Low susceptibility to hepatitis C infection ( 31206233) Macular thickness ( 30535121) Monobrow ( 27182965) Obesity-related traits ( 23251661) PR interval ( 30046033) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762) Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) ( 30166627) Smoking initiation (ever regular vs never regular) ( 30679032) Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306) Waist circumference ( 28552196)	Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433)
Interacting Genes		12 interacting genes: ADAT2 APC CFAP58 ING4 ING5 MORF4L1 PIAS2 PRPF3 PSTPIP1 RBM15 RBM15B RRAS	35 interacting genes: APC APLP1 ARFIP2 BARD1 C3orf62 CCDC33 CDCA7L CDK2 CDKN1A CEP126 CEP44 DEUP1 EP300 FAM118B GCSH HAP1 HGS HTT ICA1 IKZF3 JADE2 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 PCM1 PRMT5 SMARCE1 TADA3 TAF1D TP53 VIM
Entrez ID		89797	84289
HPRD ID		07385	16348
Ensembl ID		ENSG00000166833	ENSG00000168395
Uniprot IDs		A7E2D6 Q8IVL1	A0A1B0GW41 Q8WYH8
PDB IDs		2YRN	3C6W 5ME8 5MTO
Enriched GO Terms of Interacting Partners?
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