CCNC and TADA3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCNC	TADA3
Description		cyclin C	transcriptional adaptor 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mediator Complex	SAGA Complex Intracellular Nucleus Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex STAGA Complex Transcription Factor TFTC Complex Mitotic Spindle
	Molecular Function	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity	Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Nuclear Receptor Binding Protein Domain Specific Binding Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II	Mitotic Cell Cycle Regulation Of Protein Phosphorylation Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Protein Deubiquitination Intracellular Estrogen Receptor Signaling Pathway Regulation Of Histone Deacetylation Regulation Of Protein Stability Histone H3 Acetylation Histone H4 Acetylation Positive Regulation Of Transcription, DNA-templated Regulation Of Tubulin Deacetylation
Pathways		PPARA activates gene expression NOTCH1 Intracellular Domain Regulates Transcription Generic Transcription Pathway SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	HATs acetylate histones Ub-specific processing proteases
Drugs
Diseases
GWAS		Erectile dysfunction ( 30297428)
Interacting Genes		32 interacting genes: CCNH CDK3 CDK8 CRX DYDC1 ERCC3 ESR1 ESR2 FOXP2 GLYR1 GOLGA2 GPC4 HSPB1 KRT13 KRT15 KRT31 LZTS2 MBIP MCM2 MED8 MEOX2 MGST3 NEFL NMNAT1 PBXIP1 PNMA5 PUF60 RB1 TADA3 TP63 TRIM39 ZNF18	29 interacting genes: ADPGK ANKRD12 AR CCNC EIF3J EP300 ESR1 FAM107B H3-4 HEXIM2 HSPA8 ING5 KDM1A MAGEH1 MFHAS1 NR1I2 PIAS4 RARA RFX1 RXRA RXRB SAP18 SGF29 TADA2A TP53 TXNRD2 USP5 XRCC6 ZNF7
Entrez ID		892	10474
HPRD ID		00456	04252
Ensembl ID		ENSG00000112237	ENSG00000171148
Uniprot IDs		P24863 Q7Z4L3	A0A024R2D7 A8K899 O75528
PDB IDs		3RGF 4CRL 4F6S 4F6U 4F6W 4F70 4F7J 4F7L 4F7N 4F7S 4G6L 5BNJ 5CEI 5FGK 5HBE 5HBH 5HBJ 5HNB 5HVY 5I5Z 5ICP 5IDN 5IDP 5XQX 5XS2
Enriched GO Terms of Interacting Partners?
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