IER3 and PRNP

  • Number of citations of the paper that reports this interaction (PubMedID 18482256)
  • 14

IER3

PRNP

Description immediate early response 3 prion protein
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related macular degeneration ( 23455636)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Blood protein levels ( 28240269)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Decreased fine motor function in Charcot-Marie-Tooth disease 1A (eating with utensils) ( 30958311)
  • Rosacea symptom severity ( 29771307)
  • Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848)
  • Sleep duration ( 25469926)
  • Small cell lung carcinoma ( 28604730)
  • Type 1 diabetes and autoimmune thyroid diseases ( 25936594)
  • Ulcerative colitis ( 20848476)
  • Creutzfeldt-Jakob disease ( 19081515)
  • Creutzfeldt-Jakob disease (sporadic) ( 25918841)
  • Creutzfeldt-Jakob disease (variant) ( 22137330)
  • KANNO antigen negativity ( 31020675)
  • Platelet aggregation ( 20526338)
  • Prion diseases ( 22210626)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI (smoking interaction) ( 28443625)
Interacting Genes 10 interacting genes: APP AQP2 FHL2 GLP1R MAPK1 MAPK3 MDM2 PPP2R5B PPP2R5C PRNP 93 interacting genes: ABT1 ADAM23 ADAP2 AGO1 AIFM3 APBB1 APLP1 APLP2 APOE ARHGAP15 ATIC ATP6V1B2 BAG6 BAZ2B BRD2 C7orf50 CAV1 CCDC149 CIRBP CLSTN1 CLU CNP CNTN1 CRYAB CSN3 CSNK2A1 CSNK2A2 CSNK2B CWC15 DDX47 DNM1 DOCK7 DPP6 DYRK3 ERI3 FAM27E3 FBLN5 FBXO45 FGF13 FHL1 GRB2 HAX1 HSPA5 HSPD1 IER3 KIAA1191 KIFAP3 L1CAM LMNA LSAMP MAG MARK4 MMADHC MOG MTG1 NCAM1 NCAM2 NECTIN1 NHP2 NIPSNAP2 NOB1 OPCML P4HB PDE4DIP PLG PPFIBP2 PPP1R14A PSMA3 PSMB5 PTRH1 PYM1 RBM22 RNPC3 RPL41 SCNM1 SEC31A SPARCL1 STARD5 STIP1 SURF2 TBPL1 TMEM237 TRIM15 TSC22D4 TSLP TYMSOS UTP4 WDR5 WDR61 ZFYVE28 ZKSCAN8 ZNF408 ZNF740
Entrez ID 8870 5621
HPRD ID 04295 01453
Ensembl ID ENSG00000137331 ENSG00000171867
Uniprot IDs A0A1U9X7X2 P46695 F7VJQ1 P04156 Q53YK7
PDB IDs 1E1G 1E1J 1E1P 1E1S 1E1U 1E1W 1FKC 1FO7 1H0L 1HJM 1HJN 1I4M 1OEH 1OEI 1QLX 1QLZ 1QM0 1QM1 1QM2 1QM3 2IV4 2IV5 2IV6 2K1D 2KUN 2LBG 2LEJ 2LFT 2LSB 2LV1 2M8T 2OL9 2W9E 3HAF 3HAK 3HEQ 3HER 3HES 3HJ5 3HJX 3MD4 3MD5 3NHC 3NHD 3NVF 4DGI 4E1H 4E1I 4KML 4N9O 5L6R 5YJ4 5YJ5 6DU9
Enriched GO Terms of Interacting Partners?
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