CCKBR and NTM

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCKBR	NTM
Description		cholecystokinin B receptor	neurotrimin
Image
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Membrane	Extracellular Region Plasma Membrane Anchored Component Of Membrane
	Molecular Function	Cholecystokinin Receptor Activity Protein Binding Gastrin Receptor Activity Peptide Hormone Binding Type B Gastrin/cholecystokinin Receptor Binding 1-phosphatidylinositol-3-kinase Regulator Activity	Protein Binding
	Biological Process	Gastric Acid Secretion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Cell Proliferation Cholecystokinin Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase Activity PH Reduction Digestive Tract Development Gland Development	Cell Adhesion Neuron Recognition
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events Gastrin-CREB signalling pathway via PKC and MAPK	Post-translational modification: synthesis of GPI-anchored proteins
Drugs		Pentagastrin
Diseases
GWAS		Diastolic blood pressure ( 30224653) Early spontaneous preterm birth ( 31194736) Gastroesophageal reflux disease ( 31527586)	Aggressiveness in attention deficit hyperactivity disorder ( 27021288) Asperger disorder ( 21182207) Blood protein levels ( 30072576) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Familial lung adenocarcinoma ( 29924316) Feeling worry ( 29500382) Food addiction ( 27106561) Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Glucocorticoid-induced osteonecrosis (time dependent analysis) ( 26265699) Gut microbiota (functional units) ( 27694959) Intake of total sugars ( 31005972) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Male fertility ( 22633400) Mental health study participation (completed survey) ( 31263887) Myopia ( 27182965) Obesity-related traits ( 23251661) Plasma anti-thyroglobulin levels ( 29678681) Pre-treatment viral load in HIV-1 infection ( 31219150) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Sunburns ( 23548203)
Interacting Genes		7 interacting genes: ADRB2 ATP13A2 CCK CCKAR NTM PPP1R9B PTPN11	7 interacting genes: APP C19orf47 CCKBR KRTAP3-2 KRTAP5-9 LSAMP NEGR1
Entrez ID		887	50863
HPRD ID		00323	06398
Ensembl ID		ENSG00000110148	ENSG00000182667
Uniprot IDs		E9PIC8 P32239	B7Z1I4 Q9P121
PDB IDs		1L4T	6DLF
Enriched GO Terms of Interacting Partners?
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