LDB1 and LMO3

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LDB1	LMO3
Description		LIM domain binding 1	LIM domain only 3
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cell Leading Edge Protein-containing Complex Beta-catenin-TCF Complex	Cytoplasm
	Molecular Function	RNA Polymerase II Activating Transcription Factor Binding Transcription Corepressor Activity Protein Binding Enzyme Binding LIM Domain Binding Protein Homodimerization Activity	Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Transcription, DNA-templated Regulation Of Transcription, DNA-templated Multicellular Organism Development Neuron Differentiation Regulation Of Cell Migration Regulation Of DNA-templated Transcription, Elongation Regulation Of Kinase Activity Histone H3-K4 Acetylation Negative Regulation Of Erythrocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Hemoglobin Biosynthetic Process Regulation Of Focal Adhesion Assembly Regulation Of Hematopoietic Stem Cell Differentiation	Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Fat Cell Differentiation Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Glucocorticoid Receptor Signaling Pathway
Pathways		RUNX1 regulates transcription of genes involved in differentiation of HSCs Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Pulse pressure ( 30578418)	Chronotype ( 30696823) Household income (MTAG) ( 31844048) Tourette syndrome ( 30818990) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		27 interacting genes: ATXN1 CTDSP1 DNMT3L ESR1 IRAK3 ISL1 LHX2 LHX3 LHX8 LMO1 LMO2 LMO3 LMO4 LMX1A LMX1B LSM7 POLR1B PSMA1 PSMD10 RLIM SP1 SSBP1 SSBP2 SSBP3 SSBP4 TOLLIP UPF1	37 interacting genes: AIMP2 BANP BEND7 CARF CBY2 CCDC33 CCDC85B CEP170P1 CEP57L1 DVL2 FAM131C FBLIM1 FOS GABPB1 GOLGA2 HNRNPC HNRNPM IKZF1 KCTD1 KXD1 LDB1 LDB2 MBIP MDFI NBPF22P NHLH2 NUTM1 PHC2 PNMA1 RALYL RFX6 RORA SAMD3 SP4 TAX1BP1 ZBTB43 ZBTB8A
Entrez ID		8861	55885
HPRD ID		09144	11832
Ensembl ID		ENSG00000198728	ENSG00000048540
Uniprot IDs		Q86U70	A0A024RAT1 Q8TAP4 Q9NYC6
PDB IDs		2XJY 2XJZ 2YPA
Enriched GO Terms of Interacting Partners?
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