SAP30 and SAMSN1

Number of citations of the paper that reports this interaction (PubMedID 20478393)
5

Data Source:
BioGRID (affinity chromatography technology, pull down)

		SAP30	SAMSN1
Description		Sin3A associated protein 30	SAM domain, SH3 domain and nuclear localization signals 1
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GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleoplasm	Ruffle Nucleus Cytoplasm Cytosol
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity Histone Deacetylase Activity Protein Binding Metal Ion Binding	Phosphotyrosine Residue Binding RNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Histone Deacetylation Skeletal Muscle Cell Differentiation	Negative Regulation Of Adaptive Immune Response Negative Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of B Cell Activation
Pathways		HDACs deacetylate histones NoRC negatively regulates rRNA expression
Drugs
Diseases
GWAS			Coronary atherosclerosis (increased number of diseased vessels) (traffic exposure interaction) ( 28355232) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes		26 interacting genes: BRMS1 BRMS1L CIR1 CYTOR H2AC16 H2BC21 H3-4 H4-16 HBP1 HDAC1 HDAC2 HTT ID3 ING1 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A YY1 ZNF395	10 interacting genes: FASLG NEDD4 PILRB SAP30 SFN YWHAB YWHAE YWHAH YWHAQ YWHAZ
Entrez ID		8819	64092
HPRD ID		04540	06413
Ensembl ID		ENSG00000164105	ENSG00000155307
Uniprot IDs		O75446	Q9NSI8 S6FRS6
PDB IDs		2KDP	6UZJ
Enriched GO Terms of Interacting Partners?
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