SNX4 and PTPN5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		SNX4	PTPN5
Description		sorting nexin 4	protein tyrosine phosphatase non-receptor type 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoplasmic Dynein Complex Plasma Membrane Membrane SNARE Complex Early Endosome Membrane Protein-containing Complex	Nucleoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Transferrin Receptor Binding Leptin Receptor Binding	Phosphotyrosine Residue Binding Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Protein Transport Endocytic Recycling Positive Regulation Of Histamine Secretion By Mast Cell	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Cellular Response To Cytokine Stimulus
Pathways			Interleukin-37 signaling
Drugs
Diseases
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708) Urate levels ( 31578528)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065) Myopia ( 27182965)
Interacting Genes		15 interacting genes: AGK ARL6IP1 ATP6V0A1 BIN1 EGFR HIVEP1 INSR LEPR MAGEA6 PDGFRA PDGFRB PTPN5 SNX2 SNX6 SUPT5H	14 interacting genes: CCNQ CUL5 CXCL9 FYN MAPK1 MAPK3 MOB1A PRKN SAAL1 SNX4 TERF1 TMEM51 VTI1B ZBTB5
Entrez ID		8723	84867
HPRD ID		09334	01472
Ensembl ID		ENSG00000114520	ENSG00000110786
Uniprot IDs		O95219	B7Z2F8 P54829 Q86TL3
PDB IDs			2BIJ 2BV5 2CJZ 5OVR 5OVX 5OW1 6H8R
Enriched GO Terms of Interacting Partners?
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