VAMP8 and STX3

Number of citations of the paper that reports this interaction (PubMedID 10336434)
103

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		VAMP8	STX3
Description		vesicle associated membrane protein 8	syntaxin 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Early Endosome Cytosol Plasma Membrane Membrane Integral Component Of Membrane Clathrin-coated Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane SNARE Complex Early Endosome Membrane Late Endosome Membrane Vesicle Azurophil Granule Membrane Specific Granule Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Tertiary Granule Membrane Mucin Granule	Vacuole Plasma Membrane Cell-cell Junction Synaptic Vesicle Endomembrane System Integral Component Of Membrane Apical Plasma Membrane Lamellipodium Dendrite Growth Cone SNARE Complex Melanosome Specific Granule Azurophil Granule Zymogen Granule Membrane Presynaptic Membrane Neuron Projection Presynaptic Active Zone Membrane Extracellular Exosome Schaffer Collateral - CA1 Synapse Postsynapse Glutamatergic Synapse
	Molecular Function	SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity Syntaxin Binding	SNARE Binding SNAP Receptor Activity Protein Binding Arachidonic Acid Binding
	Biological Process	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Post-Golgi Vesicle-mediated Transport Vesicle Fusion Protein Transport Autophagosome Membrane Docking SNARE Complex Assembly Eosinophil Degranulation Neutrophil Degranulation Viral Entry Into Host Cell Membrane Organization Mucus Secretion Autophagosome Maturation Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Secretion By Cell Positive Regulation Of Histamine Secretion By Mast Cell	Intracellular Protein Transport Exocytosis Vesicle Fusion Positive Regulation Of Cell Proliferation Synaptic Vesicle Docking Cytokine-mediated Signaling Pathway Neuron Projection Development Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Positive Regulation Of Cell Adhesion Vesicle Docking Positive Regulation Of Chemotaxis Long-term Synaptic Potentiation Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface
Pathways		ER-Phagosome pathway trans-Golgi Network Vesicle Budding Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Other interleukin signaling
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778 26343387) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Eosinophil counts ( 27863252) Myocardial infarction ( 26343387) Prostate cancer ( 21743467) Sum eosinophil basophil counts ( 27863252)	High chromosomal aberration frequency (chromosome type) ( 31586183)
Interacting Genes		12 interacting genes: CDC25A MLH1 NAPA SNAP23 SNAP25 STX1A STX3 STX4 STX7 UBE2G2 VAMP2 VAMP3	20 interacting genes: CPLX2 DNAJC5 EVI5 LMNA NAPB SNAP23 SNAP25 SNAP29 STX4 STXBP1 STXBP2 SYT1 SYT4 SYT7 TBC1D30 TRPC3 TXLNA VAMP3 VAMP7 VAMP8
Entrez ID		8673	6809
HPRD ID		04415	15985
Ensembl ID		ENSG00000118640	ENSG00000166900
Uniprot IDs		B8ZZT4 Q9BV40	Q13277 Q53YE2
PDB IDs		4WY4
Enriched GO Terms of Interacting Partners?
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