EIF3B and PAIP1

Number of citations of the paper that reports this interaction (PubMedID 24396066)
12

Data Source:
BioGRID (pull down)

		EIF3B	PAIP1
Description		eukaryotic translation initiation factor 3 subunit B	poly(A) binding protein interacting protein 1
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GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Synapse Extracellular Exosome Eukaryotic Translation Initiation Factor 3 Complex, EIF3m	Cytoplasm Cytosol
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding Translation Initiation Factor Binding Molecular Adaptor Activity	RNA Binding Protein Binding Translation Activator Activity
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Regulation Of Translational Initiation IRES-dependent Viral Translational Initiation Viral Translational Termination-reinitiation	Translational Initiation Regulation Of Translational Initiation Positive Regulation Of Translation MRNA Stabilization
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	Deadenylation of mRNA
Drugs
Diseases
GWAS		Dimensional psychopathology (Social) ( 29496196)	Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes		10 interacting genes: BRCA1 EIF3A EIF3G EIF3I EIF3J EIF4G1 IL2RB PAIP1 RPS6KB1 UPF1	6 interacting genes: EIF3A EIF3B EIF4A1 PABPC1 UBR5 WWP2
Entrez ID		8662	10605
HPRD ID		06795	05539
Ensembl ID		ENSG00000106263	ENSG00000172239
Uniprot IDs		A0A024R821 A4D210 P55884	Q9H074
PDB IDs		2KRB 2NLW 5K1H	1JH4 3NTW 3RK6
Enriched GO Terms of Interacting Partners?
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