RGS20 and PTGER3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RGS20	PTGER3
Description		regulator of G protein signaling 20	prostaglandin E receptor 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Trans-Golgi Network Plasma Membrane	Cell Nuclear Envelope Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding	Prostaglandin E Receptor Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Death Intestine Smooth Muscle Contraction Positive Regulation Of Fever Generation Negative Regulation Of Gastric Acid Secretion
Pathways		G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events	Prostanoid ligand receptors G alpha (i) signalling events
Drugs			Bimatoprost Dinoprostone Misoprostol Gemeprost Limaprost
Diseases
GWAS		Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Serum uric acid levels ( 29559957) Urinary albumin-to-creatinine ratio ( 26631737)	Dental caries (decayed, missing and filled teeth) ( 31533690) Intelligence (MTAG) ( 29326435) Verbal declarative memory ( 25648963)
Interacting Genes		34 interacting genes: ABHD17A ADRB2 AQP1 CATSPER1 CRCT1 CREB5 FASLG GLRX3 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 HSPD1 INS KIF1A KLHL38 KRTAP4-2 KRTAP5-6 KRTAP5-9 LCE1B LCE2A LCE2D LCE3E LCE4A MAPKBP1 NECTIN3 OSTM1 OTX1 PTGER3 PTPMT1 STMN2 TBC1D16	23 interacting genes: ADAMTSL4 CCDC33 CDA EFEMP2 INCA1 KRT31 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MEOX2 MGAT5B MKLN1 NOTCH2NLA PTGER1 REL RGS17 RGS20 SPRY2 TCF4 TRIM42
Entrez ID		8601	5733
HPRD ID		06225	08906
Ensembl ID		ENSG00000147509	ENSG00000050628
Uniprot IDs		B3KSW4 H9NIM5 O76081	O00325 P43115
PDB IDs			6AK3 6M9T
Enriched GO Terms of Interacting Partners?
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