TCAP and SIVA1

Number of citations of the paper that reports this interaction (PubMedID 18849585)
6

Data Source:
BioGRID (two hybrid, pull down)

		TCAP	SIVA1
Description		titin-cap	SIVA1 apoptosis inducing factor
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Z Disc I Band	Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Structural Constituent Of Muscle Protein Binding, Bridging Titin Binding BMP Binding Ion Channel Binding FATZ Binding Titin Z Domain Binding	Virus Receptor Activity Tumor Necrosis Factor Receptor Binding CD27 Receptor Binding Protein Binding Metal Ion Binding
	Biological Process	Somitogenesis Skeletal Muscle Contraction Cardiac Muscle Hypertrophy Adult Heart Development Cardiac Muscle Hypertrophy In Response To Stress Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly Otic Vesicle Formation Response To Muscle Stretch Detection Of Muscle Stretch Sarcomere Organization Cardiac Muscle Fiber Development Sarcomerogenesis Detection Of Mechanical Stimulus Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction Protein-containing Complex Assembly	Viral Entry Into Host Cell Extrinsic Apoptotic Signaling Pathway
Pathways		Striated Muscle Contraction
Drugs			Zinc
Diseases		Limb-girdle muscular dystrophy (LGMD)
GWAS		Alcohol consumption ( 31358974) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Pancreatic ductal adenocarcinoma ( 30541042) Ulcerative colitis ( 20228799)	Endometrial cancer ( 27135401) Endometrial endometrioid carcinoma ( 27135401)
Interacting Genes		17 interacting genes: ANKRD2 ATXN1 CRK FAS FYN HSPB2 LHX4 MDM2 MSTN MYOZ1 MYOZ3 PDPK1 RELA SIVA1 TRIM55 TRIM63 TTN	20 interacting genes: ABL2 APP BAG5 BCL2L1 BEX3 CD27 CD4 CDKN2A MEFV NEDD4 NEDD4L PCNA POLR2M PXMP2 RAD18 RHOU SSBP3 TCAP TNFRSF4 UBE2D1
Entrez ID		8557	10572
HPRD ID		05133	16124
Ensembl ID		ENSG00000173991	ENSG00000184990
Uniprot IDs		A2TDC0 O15273	O15304
PDB IDs		1YA5 2F8V
Enriched GO Terms of Interacting Partners?
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