AP3B1 and RNGTT

		AP3B1	RNGTT
Description		adaptor related protein complex 3 subunit beta 1	RNA guanylyltransferase and 5'-phosphatase
Image		No pdb structure
GO Annotations	Cellular Component	Cell Lysosomal Membrane Golgi Apparatus Membrane AP-3 Adaptor Complex Clathrin Adaptor Complex Clathrin-coated Vesicle Membrane Synapse Axon Cytoplasm	Nucleus Nucleoplasm
	Molecular Function	Protein Phosphatase Binding GTP-dependent Protein Binding	MRNA Guanylyltransferase Activity Polynucleotide 5'-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding GTP Binding Protein Tyrosine/serine/threonine Phosphatase Activity RNA Guanylyltransferase Activity Triphosphatase Activity
	Biological Process	Protein Targeting To Lysosome Intracellular Protein Transport Blood Coagulation Anterograde Axonal Transport Synaptic Vesicle Budding From Endosome Vesicle-mediated Transport Melanosome Organization Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Positive Regulation Of NK T Cell Differentiation	Transcription By RNA Polymerase II 7-methylguanosine MRNA Capping RNA Processing Viral Process Peptidyl-tyrosine Dephosphorylation Polynucleotide 5' Dephosphorylation
Pathways		Golgi Associated Vesicle Biogenesis Signaling by BRAF and RAF fusions	RNA Pol II CTD phosphorylation and interaction with CE during HIV infection mRNA Capping RNA Pol II CTD phosphorylation and interaction with CE
Drugs			Isopropyl Alcohol
Diseases		Hermansky-Pudlak syndrome (HPS)
GWAS		FEV1 ( 30804560) Insulin resistance/response ( 21901158) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609 30804560) Metabolite levels ( 23823483) Triglycerides ( 26780889) Type 2 diabetes ( 31049640)	Colorectal or endometrial cancer ( 26621817) Depression in smokers ( 30219690) Height ( 31562340) Response to statin therapy ( 20339536) Simvastatin-induced myopathy ( 31220337) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		19 interacting genes: AP3D1 AP3S2 ARF1 ARF5 ARF6 ARR3 ATM ATR BUB1 BUB1B CLTC CSNK1A1 CXADR FCGR2B GKAP1 RNGTT SLC30A3 SSBP2 ZER1	2 interacting genes: AP3B1 RNMT
Entrez ID		8546	8732
HPRD ID		04551	04621
Ensembl ID		ENSG00000132842	ENSG00000111880
Uniprot IDs		A0A0S2Z5J4 O00203	B4DSJ8 O60942 Q7Z3R6
PDB IDs			2C46 3S24
Enriched GO Terms of Interacting Partners?
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