KRTAP4-2 and PRKAG1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KRTAP4-2	PRKAG1
Description		keratin associated protein 4-2	protein kinase AMP-activated non-catalytic subunit gamma 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Nucleoplasm Cytosol Membrane Nucleotide-activated Protein Kinase Complex
	Molecular Function	Protein Binding	Protein Kinase Activity CAMP-dependent Protein Kinase Activity Protein Binding ATP Binding CAMP-dependent Protein Kinase Regulator Activity AMP Binding Protein Kinase Regulator Activity Protein Kinase Binding ADP Binding
	Biological Process	Keratinization	Regulation Of Glycolytic Process Protein Phosphorylation Fatty Acid Biosynthetic Process Cell Cycle Arrest Signal Transduction Spermatogenesis Positive Regulation Of Gene Expression Macroautophagy Regulation Of Macroautophagy Positive Regulation Of Protein Kinase Activity Import Into Nucleus Regulation Of Signal Transduction By P53 Class Mediator Regulation Of CAMP-dependent Protein Kinase Activity
Pathways		Keratinization	Translocation of SLC2A4 (GLUT4) to the plasma membrane Macroautophagy Activation of PPARGC1A (PGC-1alpha) by phosphorylation Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of TP53 Activity through Phosphorylation Lipophagy Activation of AMPK downstream of NMDARs
Drugs			Acetylsalicylic acid
Diseases
GWAS			Bipolar disorder ( 31043756) Body mass index ( 29273807) HDL cholesterol ( 30275531) Pulse pressure ( 27618447) Systolic blood pressure ( 27618447 30578418)
Interacting Genes		75 interacting genes: ADAMTSL4 ALDH3B1 AMOTL2 AQP1 ATG9A AXIN1 BYSL CHIC2 CHRD CRCT1 CREB5 DLGAP2 DOCK2 FAM74A4 GLRX3 GNMT HOXA1 HPCAL1 HSD3B7 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LASP1 LCE1B LCE2A LCE3C LCE3E LCE4A LNX1 MEOX2 NECTIN3 NLK NOTCH2NLA NR1D2 NTAQ1 NUFIP2 OTX1 PDE9A PGLS PIN1 PLSCR1 POM121L8P PRKAB2 PRKAG1 PSMA6 RASSF5 RGS20 SDC3 SHFL SLC23A1 SLC25A10 SPATA24 SPATA3 SPRY1 TCEANC TINAGL1 TRIM42 TXNDC5 TYRO3 ZBTB24 ZNF124 ZNF20 ZNF417 ZNF559 ZNF581 ZNF688	16 interacting genes: ACACA AP1S3 C1orf94 CBS EIF3G KCNN4 KEAP1 KRTAP10-3 KRTAP4-2 PAICS PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG2 TEKT1
Entrez ID		85291	5571
HPRD ID		13944	04118
Ensembl ID		ENSG00000244537	ENSG00000181929
Uniprot IDs		Q9BYR5	A0A024R125 P54619
PDB IDs			2UV4 2UV5 2UV6 2UV7 4CFE 4CFF 4RER 4REW 4ZHX 5EZV 5ISO 6B1U 6B2E 6C9F 6C9G 6C9H 6C9J
Enriched GO Terms of Interacting Partners?
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