UBASH3B and SLC25A48

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		UBASH3B	SLC25A48
Description		ubiquitin associated and SH3 domain containing B	solute carrier family 25 member 48
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Mitochondrial Inner Membrane Integral Component Of Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Phosphoprotein Binding	Protein Binding Acyl Carnitine Transmembrane Transporter Activity
	Biological Process	Negative Regulation Of Protein Kinase Activity Negative Regulation Of Signal Transduction Peptidyl-tyrosine Dephosphorylation Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Collagen-activated Signaling Pathway Regulation Of Protein Binding Regulation Of Osteoclast Differentiation Negative Regulation Of Osteoclast Differentiation Negative Regulation Of Bone Resorption Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Platelet Aggregation Negative Regulation Of Platelet Aggregation	Acyl Carnitine Transport Amino Acid Transport Acyl Carnitine Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Blood urea nitrogen levels ( 31152163) Cholesterol, total ( 24097068 25961943 20686565) Chronotype ( 30696823) Diastolic blood pressure ( 30224653) Eye length ( 30174134) HDL cholesterol ( 24097068 20686565) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376) Pemphigus vulgaris ( 29857070) Stroke ( 26089329) Systolic blood pressure ( 30578418) Total cholesterol levels ( 28334899)	Cerebrospinal fluid p-tau levels in Alzheimer's disease dementia ( 29274321) Cerebrospinal fluid t-tau levels ( 29274321) Obesity-related traits ( 23251661) Resistance to Mycobacterium tuberculosis in HIV-positive individuals measured by a negative tuberculin skin test (continuous) ( 28628665) Resistance to Mycobacterium tuberculosis in HIV-positive individuals measured by a negative tuberculin skin test (dichotomous) ( 28628665)
Interacting Genes		27 interacting genes: CBL CBLB CUL3 DAZAP2 DMRT3 DOC2A FAM168A JAK2 KHDRBS1 MAP3K1 PKP4 PRKN RCHY1 RNF41 SHC1 SLC25A48 SPRY2 SYK UBB UBC UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H VPS37B	6 interacting genes: KRTAP10-3 KRTAP10-7 MID2 PNMA1 TRAF1 UBASH3B
Entrez ID		84959	153328
HPRD ID		16463	14098
Ensembl ID		ENSG00000154127	ENSG00000145832
Uniprot IDs		Q8TF42	Q6ZT89
PDB IDs		2CPW 2E5K 5VR6 5W5G
Enriched GO Terms of Interacting Partners?
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