PRRC2B and DPY30

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

		PRRC2B	DPY30
Description		proline rich coiled-coil 2B	dpy-30 histone methyltransferase complex regulatory subunit
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Golgi Apparatus Trans-Golgi Network Histone Methyltransferase Complex MLL3/4 Complex Set1C/COMPASS Complex
	Molecular Function	RNA Binding Protein Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Cell Differentiation	Endosomal Transport Regulation Of Megakaryocyte Differentiation Histone H3-K4 Methylation
Pathways			PKMTs methylate histone lysines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS		Urate levels ( 31578528)	Inflammatory biomarkers ( 24182552) Interleukin-18 levels ( 31584380) Male-pattern baldness ( 28196072)
Interacting Genes		18 interacting genes: AK8 APP ATN1 ATXN1 ATXN1L CFAP77 CRK DDX31 DNAJC5 DPY30 EHMT2 FBXO7 GTF3C4 PLPP7 RERE SETX SRPK2 UCK1	14 interacting genes: ARFGEF1 ASH2L CHMP2B DYDC1 GTF2I H3-4 KMT2C OTX1 PRPF3 PRRC2B PSMD14 SETD1A TMCC2 UBC
Entrez ID		84726	84661
HPRD ID		13805	17434
Ensembl ID		ENSG00000130723	ENSG00000162961
Uniprot IDs		Q5JSZ5 Q9BU62	B4DIS3 Q9C005
PDB IDs			3G36 4RIQ 4RT4 4RTA 6E2H
Enriched GO Terms of Interacting Partners?
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