GTPBP3 and PFKL

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		GTPBP3	PFKL
Description		GTP binding protein 3, mitochondrial	phosphofructokinase, liver type
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion	Extracellular Region Cytosol 6-phosphofructokinase Complex Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	GTPase Activity Protein Binding GTP Binding	6-phosphofructokinase Activity Protein Binding ATP Binding AMP Binding Kinase Binding Identical Protein Binding Metal Ion Binding Monosaccharide Binding Fructose Binding Fructose-6-phosphate Binding
	Biological Process	TRNA Wobble Uridine Modification TRNA Methylation Embryonic Organ Development	Fructose 6-phosphate Metabolic Process Glucose Catabolic Process Glycolytic Process Response To Glucose Fructose 1,6-bisphosphate Metabolic Process Neutrophil Degranulation Negative Regulation Of Insulin Secretion Protein Homotetramerization Canonical Glycolysis
Pathways		tRNA modification in the mitochondrion	Neutrophil degranulation Glycolysis
Drugs
Diseases
GWAS		Mitochondrial DNA copy number ( 30704525)	Rheumatoid arthritis ( 21505073)
Interacting Genes		9 interacting genes: CIC DCAF8 GNE PARP11 PFKL PRPF3 PTAFR RIBC2 SINHCAF	13 interacting genes: APP ATN1 COPS6 GTPBP3 KRTAP10-7 KRTAP4-12 KRTAP5-9 MYD88 PCNT PFKM PRPF40A TESK1 YWHAQ
Entrez ID		84705	5211
HPRD ID		12255	01385
Ensembl ID		ENSG00000130299	ENSG00000141959
Uniprot IDs		B7Z563 Q969Y2	P17858 Q7L2M7
PDB IDs
Enriched GO Terms of Interacting Partners?
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