SMARCA5 and BAZ1B

Number of citations of the paper that reports this interaction (PubMedID 11980720)
85

Data Source:
HPRD (in vitro, in vivo)

		SMARCA5	BAZ1B
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	bromodomain adjacent to zinc finger domain 1B
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GO Annotations	Cellular Component	Condensed Chromosome Fibrillar Center Nucleus Nucleoplasm Chromatin Silencing Complex NURF Complex RSF Complex Nuclear Replication Fork	Condensed Chromosome Nucleoplasm Pericentric Heterochromatin Nuclear Body Nuclear Replication Fork
	Molecular Function	DNA Binding Helicase Activity Protein Binding ATP Binding DNA-dependent ATPase Activity ATPase Activity Nucleosome Binding Histone Binding	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Zinc Ion Binding Histone Kinase Activity Histone Binding
	Biological Process	Chromatin Silencing At RDNA Nucleosome Assembly Chromatin Remodeling DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Nucleosome Positioning CENP-A Containing Nucleosome Assembly ATP-dependent Chromatin Remodeling Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Leukemia Inhibitory Factor	Chromatin Assembly Or Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Histone Phosphorylation Peptidyl-tyrosine Phosphorylation Positive Regulation Of Gene Expression, Epigenetic
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Deposition of new CENPA-containing nucleosomes at the centromere	B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Drugs		Beta-D-Glucose 4-Deoxy-Alpha-D-Glucose
Diseases
GWAS		Height ( 31562340)	C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809) Hypertriglyceridemia ( 23505323) Hyperuricemia ( 29124443) Metabolic syndrome ( 31589552) Migraine ( 27182965) Protein C levels ( 20802025) Pursuit maintenance gain ( 29064472) Serum uric acid levels ( 30993211) Triglycerides ( 20864672) Urate levels ( 23263486) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		17 interacting genes: BAZ1A BAZ1B BAZ2A CDT1 CHRAC1 CREB1 CTNNB1 DNMT3B H3-3A H3C1 H4-16 HDAC2 MAF POLE3 RAD21 RSF1 SATB1	10 interacting genes: CDT1 MTNR1A MYO1C NR4A2 PCNA SMARCA1 SMARCA5 SMARCC2 SMARCE1 SUMO2
Entrez ID		8467	9031
HPRD ID		04538	10416
Ensembl ID		ENSG00000153147	ENSG00000009954
Uniprot IDs		O60264	Q9UIG0
PDB IDs		6NE3	1F62 5NNF
Enriched GO Terms of Interacting Partners?
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