MYPN and ANKRD1

Number of citations of the paper that reports this interaction (PubMedID 11309420)
72

Data Source:
BioGRID (pull down)
HPRD (two hybrid)

		MYPN	ANKRD1
Description		myopalladin	ankyrin repeat domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Z Disc Axon I Band	Fibrillar Center Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Cytosol I Band
	Molecular Function	Actin Binding Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding Muscle Alpha-actinin Binding Cell-cell Adhesion Mediator Activity	RNA Polymerase II Transcription Factor Binding P53 Binding DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Titin Binding Histone Deacetylase Binding RNA Polymerase II Sequence-specific DNA-binding Transcription Factor Binding R-SMAD Binding
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Sarcomere Organization Dendrite Self-avoidance	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Projection Development Regulation Of Lipid Metabolic Process Cellular Response To Drug Skeletal Muscle Cell Differentiation Response To Muscle Stretch Positive Regulation Of Apoptotic Process Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Sarcomere Organization Positive Regulation Of Protein Secretion Cardiac Muscle Tissue Morphogenesis Protein Kinase C Signaling Cellular Response To Lipopolysaccharide Cellular Response To Mechanical Stimulus Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To Organic Cyclic Compound Cellular Response To Hypoxia Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of DNA Biosynthetic Process
Pathways			PPARA activates gene expression
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737) Chronic kidney disease ( 31152163) Coffee consumption ( 31046077) Creatine kinase levels ( 29403010) Creatinine levels ( 29403010) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) FEV1 ( 30804560) Glomerular filtration rate ( 29403010) Height ( 25282103) Lung function (FVC) ( 28166213 30804560) Optic nerve measurement (disc area) ( 20395239) Peak expiratory flow ( 30804560) Psoriasis ( 25854761)	Intraocular pressure ( 29617998)
Interacting Genes		7 interacting genes: ACTN2 ACTN3 ANKRD1 ANKRD23 NEB NEBL TTN	5 interacting genes: CASQ2 MYPN TRIM55 TRIM63 TTN
Entrez ID		84665	27063
HPRD ID		10536	10647
Ensembl ID		ENSG00000138347	ENSG00000148677
Uniprot IDs		A0A087WX60 Q86TC9	A0A384NYH5 Q15327
PDB IDs
Enriched GO Terms of Interacting Partners?
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