L3MBTL3 and PLEKHF2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		L3MBTL3	PLEKHF2
Description		L3MBTL histone methyl-lysine binding protein 3	pleckstrin homology and FYVE domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane
	Molecular Function	Molecular_function DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding	Protein Binding Phosphatidylinositol Binding Metal Ion Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Macrophage Differentiation Granulocyte Differentiation Erythrocyte Maturation	Protein Transport
Pathways
Drugs
Diseases
GWAS		Birth weight ( 31043758 27680694) Body mass index ( 25673413) Breast cancer ( 29059683 29058716) Breast cancer (estrogen-receptor negative) ( 29058716) C-reactive protein levels ( 30388399) Chronic kidney disease ( 31152163) Estimated glomerular filtration rate ( 31152163) Heel bone mineral density ( 30598549 28869591) Height ( 28552196 20881960 25282103 25429064 23563607 31562340 18391951) Hematocrit ( 27863252) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 28552196 25673412) Influenza A (H1N1) infection ( 26379185) Lymphocyte counts ( 27863252) Mild influenza (H1N1) infection ( 26379185) Multiple sclerosis ( 31604244 27386562) Offspring birth weight ( 31043758) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Weight ( 28552196)	Radiation response ( 20923822)
Interacting Genes		30 interacting genes: ASB6 BANP BYSL DNMT1 KDM1A LRRK2 LSM4 LZTR1 MAPK3 MAPK9 MORF4L1 MORF4L2 NGB OAZ3 PDE6G PHC2 PIK3R3 PLEKHF1 PLEKHF2 POLR2L PRKAA1 PRKAA2 SNRPB SOX2 SP100 SUMO1P1 THRA TSTD2 TTC19 ZCWPW1	71 interacting genes: ACY3 AIDA AIMP2 APP APPL1 ARL14EP BEND7 BLOC1S6 BSCL2 CAVIN2 CCDC172 CCDC85B CEP44 CGGBP1 CHIC2 DPPA4 DRAP1 DTX2 DUT ESRP1 FBXO28 FHL3 FOXA1 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HEY1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NKG7 NONO NPM2 PDP1 PEX2 PRDM14 PRKAR1A PRPSAP1 RAB39A RABAC1 RADX RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SEPTIN2 SEPTIN5 SEPTIN6 SETBP1 SFN SPEF1 TBX3 TCN2 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z USF1 ZNF250 ZNF263 ZNF398
Entrez ID		84456	79666
HPRD ID		11222	15147
Ensembl ID		ENSG00000198945	ENSG00000175895
Uniprot IDs		Q96JM7	Q9H8W4
PDB IDs		1WJQ 1WJS 3UT1 4FL6 4L59
Enriched GO Terms of Interacting Partners?
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