SYVN1 and GPR37

Number of citations of the paper that reports this interaction (PubMedID 15572843)
0

Data Source:
BioGRID (enzymatic study)

		SYVN1	GPR37
Description		synoviolin 1	G protein-coupled receptor 37
Image			No pdb structure
GO Annotations	Cellular Component	Hrd1p Ubiquitin Ligase Complex Hrd1p Ubiquitin Ligase ERAD-L Complex Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Smooth Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane Derlin-1 Retrotranslocation Complex Endoplasmic Reticulum Quality Control Compartment	Ubiquitin Ligase Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex
	Molecular Function	Protein Binding Metal Ion Binding Unfolded Protein Binding Chaperone Binding ATPase Binding Ubiquitin Protein Ligase Activity Ubiquitin-specific Protease Binding	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Hsp70 Protein Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Prosaposin Receptor Activity Peptide Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol IRE1-mediated Unfolded Protein Response ERAD Pathway Protein Stabilization Protein K48-linked Ubiquitination Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Endoplasmic Reticulum Mannose Trimming	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Locomotion Involved In Locomotory Behavior Dopamine Biosynthetic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Dopamine Metabolic Process Negative Regulation Of Hydrogen Peroxide-induced Cell Death
Pathways		XBP1(S) activates chaperone genes Hedgehog ligand biogenesis Hh mutants that don't undergo autocatalytic processing are degraded by ERAD ER Quality Control Compartment (ERQC)	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS		Blood protein levels ( 28240269)	Ankylosing spondylitis ( 23749187) Cutaneous malignant melanoma ( 26237428) Reading and spelling ( 23738518)
Interacting Genes		13 interacting genes: APP ATN1 ATP6AP1 CLU ERN1 GPR37 TP53 UBE2D2 UBE2D3 UBE2G1 UBE2U UBE2Z USP7	9 interacting genes: ADRB2 GABARAPL2 GLP1R GRIP1 HSPA1A PRKN SDCBP STUB1 SYVN1
Entrez ID		84447	2861
HPRD ID		07618	03992
Ensembl ID		ENSG00000162298	ENSG00000170775
Uniprot IDs		Q86TM6	O15354
PDB IDs		6A3Z
Enriched GO Terms of Interacting Partners?
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