TCHP and KRT8

Number of citations of the paper that reports this interaction (PubMedID 15731013)
22

Data Source:
HPRD (two hybrid)

		TCHP	KRT8
Description		trichoplein keratin filament binding	keratin 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Centrosome Cytosol Plasma Membrane Desmosome Keratin Filament Apical Cortex Ciliary Transition Fiber	Nucleus Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cell-cell Junction Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Nuclear Matrix Z Disc Sarcolemma Costamere Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Protein-containing Complex Binding Scaffold Protein Binding
	Biological Process	Apoptotic Process Cell Projection Organization Negative Regulation Of Cell Growth Negative Regulation Of Cilium Assembly	Viral Process Keratinization Tumor Necrosis Factor-mediated Signaling Pathway Sarcomere Organization Response To Hydrostatic Pressure Response To Other Organism Cell Differentiation Involved In Embryonic Placenta Development Cornification Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process
Pathways			Keratinization Formation of the cornified envelope
Drugs			Tenecteplase Copper
Diseases
GWAS		Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolite levels (MHPG) ( 23319000) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Cancer (pleiotropy) ( 27197191) Gamma glutamyl transferase levels ( 29403010) Prostate cancer ( 21743057)
Interacting Genes		23 interacting genes: CCDC172 CCDC85B CDR2 DYDC1 IFFO1 KCTD17 KRT14 KRT15 KRT16 KRT18 KRT40 KRT5 KRT6A KRT8 LZTS2 MIPOL1 MKRN3 NAB2 NDOR1 NME7 TEX11 TRIM27 VIM	35 interacting genes: ANXA1 BYSL CLK1 DEDD DMD EGFR ELOC ESR1 FBXO25 FGFR3 GRB2 HSPA5 IKBKG KPNA2 KRT13 KRT15 KRT18 KRT31 KRT38 KRT40 MAPK1 MAPK14 MAPK3 MAPK8 PKD1 PKP1 PLAT PNN PPL QRSL1 RAF1 TCHP TFIP11 TROAP WBP2
Entrez ID		84260	3856
HPRD ID		14403	01015
Ensembl ID		ENSG00000139437	ENSG00000170421
Uniprot IDs		A0A024RBM9 Q9BT92	P05787 Q7L4M3
PDB IDs
Enriched GO Terms of Interacting Partners?
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