CASP8 and HDAC7

  • Number of citations of the paper that reports this interaction (PubMedID 18458084)
  • 18
  • Data Source:
  • BioGRID (enzymatic study)

CASP8

HDAC7

Description caspase 8 histone deacetylase 7
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Asthma ( 31361310 30929738)
  • Asthma (adult onset) ( 31036433 30929738)
  • Bipolar disorder ( 31043756)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)
  • Diastolic blood pressure ( 27841878)
  • Inflammatory bowel disease ( 28067908)
  • Lymphocyte counts ( 27863252)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Obesity-related traits ( 23251661)
  • Platelet count ( 27863252)
  • Plateletcrit ( 27863252)
  • Primary sclerosing cholangitis ( 23603763)
  • Systolic blood pressure ( 27841878)
  • Ulcerative colitis ( 28067908)
  • Urate levels ( 23263486)
Interacting Genes 127 interacting genes: AGR3 ANGPTL4 APAF1 APP AR ATAD2 ATG4D ATP1A3 BAP1 BCAP31 BCL2 BCL2L1 BCL2L10 BEX1 BFAR BID BIRC6 BLID CASC3 CASP1 CASP10 CASP14 CASP2 CASP3 CASP4 CASP6 CASP7 CASP8AP2 CASP9 CDH1 CDH13 CDK11B CDKN1B CFLAR CHD3 CHUK CNBP COPS6 CRADD CTNNB1 DEDD DEDD2 EDA2R EIF2AK2 EPSTI1 ERRFI1 FADD FAF1 FAS FYN GLCE GMEB1 GREB1 GRIA1 GZMB HBP1 HDAC7 HECTD3 HIP1 IKBKB IKBKG IL13RA2 IL24 ILK KLK5 KLK9 KRT18 LYPD3 MAP1LC3B MAP3K14 MAP4K4 MAPK1 MAPK3 MAPT NOD1 NOL3 NR1H4 NSD3 PARK7 PARP1 PARP2 PCYT1A PDIA6 PEA15 PIAS1 PICALM PIK3C3 PLA2G4B PLEC PLIN4 PRDM14 PRDX6 PRKCI PRKCZ PRKN PRSS50 PSEN1 PSEN2 PSMC3IP QDPR RALBP1 RB1 RIPK1 RIPK2 RYBP S100A14 SCGB2A2 SERPINB5 SNRPD3 SOX2 SRF ST14 STK24 SUMO1 TFCP2 TNFRSF10A TNFRSF10B TOPORS TRAF1 TRAF2 TRAF6 UBC UMPS USO1 VIM VPS45 YBX1 29 interacting genes: ACTN4 BCL6 CALCOCO2 CASP8 EDNRA EGFR GNMT HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 KAT5 MARK2 MARK3 MEF2A MEF2C NCOR2 PPARD PRKD1 PRKD2 REL RIPPLY1 RUNX2 SIN3A UBE2I YWHAG YWHAQ ZBTB16
Entrez ID 841 51564
HPRD ID 03459 09133
Ensembl ID ENSG00000064012 ENSG00000061273
Uniprot IDs A0A024R3Z8 Q14790 Q8WUI4
PDB IDs 1F9E 1I4E 1QDU 1QTN 2C2Z 2FUN 2K7Z 2Y1L 3H11 3KJN 3KJQ 4JJ7 4PRZ 4PS1 4ZBW 5H31 5H33 5JQE 5L08 6AGW 3C0Y 3C0Z 3C10 3ZNR 3ZNS
Enriched GO Terms of Interacting Partners?
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