FERMT3 and LIMS1

Number of citations of the paper that reports this interaction (PubMedID 25086068)
20

Data Source:
BioGRID (pull down)

		FERMT3	LIMS1
Description		fermitin family member 3	LIM zinc finger domain containing 1
Image
GO Annotations	Cellular Component	Podosome Extracellular Region Membrane Cell Junction Platelet Alpha Granule Lumen Cell Projection Extracellular Exosome	Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Perinuclear Region Of Cytoplasm
	Molecular Function	Integrin Binding	Protein Binding Zinc Ion Binding Protein Kinase Binding
	Biological Process	Platelet Degranulation Leukocyte Cell-cell Adhesion Integrin-mediated Signaling Pathway Positive Regulation Of Cell Migration Integrin Activation Regulation Of Cell-cell Adhesion Mediated By Integrin Substrate Adhesion-dependent Cell Spreading Platelet Aggregation	Epithelial To Mesenchymal Transition Cell Aging Positive Regulation Of Gene Expression Positive Regulation Of Cell-substrate Adhesion Tumor Necrosis Factor-mediated Signaling Pathway Cell Junction Assembly Positive Regulation Of GTPase Activity Establishment Of Protein Localization Cell-cell Junction Organization Negative Regulation Of Transcription, DNA-templated Regulation Of Epithelial Cell Proliferation Positive Regulation Of Focal Adhesion Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Cell-cell Adhesion Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways		Platelet degranulation	Cell-extracellular matrix interactions Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Drugs
Diseases		Leukocyte adhesion deficiency (LAD), including the following four diseases: Leukocyte adhesion deficiency (I); Leukocyte adhesion deficiency (II); Leukocyte adhesion deficiency (III); LAD with Rac2 deficiency
GWAS		Attention deficit hyperactivity disorder ( 21784300) Crohn's disease ( 28067908) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401)	Beard thickness ( 26926045) Birth weight ( 31043758) Excessive hairiness ( 29895819) Eyebrow thickness ( 26926045) LDL cholesterol ( 30275531) Monobrow thickness ( 26926045) Scalp hair shape ( 26926045)
Interacting Genes		9 interacting genes: APP EXOSC10 ILK ITGB1 LIMS1 LSM8 PARVA TINF2 TRIM15	14 interacting genes: DAPK1 EHMT2 FERMT2 FERMT3 ILK LPXN MBIP NCK2 PARVA RBBP8 RSU1 SMURF1 TGFBR1 TMSB4X
Entrez ID		83706	3987
HPRD ID		07440	03978
Ensembl ID		ENSG00000149781	ENSG00000169756
Uniprot IDs		Q86UX7	P48059
PDB IDs		2YS3	1G47 1NYP 1U5S 2COR 2D8X 2KBX 3F6Q 4HI8 4HI9 6MIF
Enriched GO Terms of Interacting Partners?
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