INO80B and UIMC1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		INO80B	UIMC1
Description		INO80 complex subunit B	ubiquitin interaction motif containing 1
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Ino80 Complex	Nucleus Nucleoplasm Nuclear Body BRCA1-A Complex
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding Histone Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding
	Biological Process	DNA Repair DNA Recombination Chromatin Remodeling Protein Deubiquitination	Double-strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Response To Ionizing Radiation Protein Deubiquitination Positive Regulation Of DNA Repair Negative Regulation Of Transcription, DNA-templated Histone H2A K63-linked Deubiquitination Signal Transduction Involved In G2 DNA Damage Checkpoint
Pathways		UCH proteinases DNA Damage Recognition in GG-NER	Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends G2/M DNA damage checkpoint
Drugs
Diseases
GWAS			Activated partial thromboplastin time ( 22703881) Menarche and menopause (age at onset) ( 19448621) Menopause (age at onset) ( 22267201 26414677 29773799) Uterine fibroids ( 31649266) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		6 interacting genes: CD81 E2F6 IGFBP2 PNMA1 SSX2IP UIMC1	20 interacting genes: ABRAXAS1 ATP8A2 BRCC3 CEP57 CREBBP DVL2 ECPAS ESR1 FANCG H2AC20 INO80B MDC1 NR6A1 SKIL TP53 UBB UBC USP13 WBP2 ZMYM3
Entrez ID		83444	51720
HPRD ID		17110	11482
Ensembl ID		ENSG00000115274	ENSG00000087206
Uniprot IDs		Q9C086	A0A024R7R0 Q96RL1
PDB IDs		6HTS	2MKF 2MKG 2N9E 2RR9
Enriched GO Terms of Interacting Partners?
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