USP9X and GPSM1

Number of citations of the paper that reports this interaction (PubMedID 20305814)
7

Data Source:
BioGRID (pull down)

		USP9X	GPSM1
Description		ubiquitin specific peptidase 9 X-linked	G protein signaling modulator 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane Growth Cone	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Protein-containing Complex
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Thiol-dependent Ubiquitinyl Hydrolase Activity Co-SMAD Binding Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity	GDP-dissociation Inhibitor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Protein Targeting To Peroxisome Cell Cycle Chromosome Segregation Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Cell Migration Protein Ubiquitination Protein Deubiquitination BMP Signaling Pathway Regulation Of Circadian Rhythm Cellular Protein Metabolic Process Rhythmic Process Axon Extension Protein Stabilization Cell Division Protein K48-linked Deubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Demethylation	Nervous System Development Positive Regulation Of Macroautophagy Cell Differentiation Negative Regulation Of GTPase Activity Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity
Pathways		Downregulation of SMAD2/3:SMAD4 transcriptional activity Ub-specific processing proteases Synthesis of active ubiquitin: roles of E1 and E2 enzymes Peroxisomal protein import Peroxisomal protein import Amyloid fiber formation	G alpha (i) signalling events
Drugs
Diseases
GWAS		Migraine ( 27322543)	Acute insulin response (insulin secretion adjusted) ( 28490609) Birth weight ( 31043758) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Insulinogenic index ( 23263489) Joint damage in rheumatoid arthritis ( 26498133) Offspring birth weight ( 31043758) Type 2 diabetes ( 30297969 29632382 26818947 23945395 31118516 30718926 28869590) Type 2 diabetes (adjusted for BMI) ( 29632382) Ulcerative colitis ( 28067908) White blood cell count ( 29403010)
Interacting Genes		21 interacting genes: AFDN ALDH1A3 BCL9 CTNNB1 DCX ERG FBXW7 GPSM1 MAP3K5 MCL1 PEX5 PSD4 RNF115 SMAD2 SMAD4 SMN2 SMURF1 STIL TDRD3 UBC VHL	12 interacting genes: CCDC158 DAZAP2 GNAI1 GNAI3 INSC KANK2 MAP1LC3A OSTM1 TRIP13 USHBP1 USP9X ZBED1
Entrez ID		8239	26086
HPRD ID		02091	17075
Ensembl ID		ENSG00000124486	ENSG00000160360
Uniprot IDs		Q6P468 Q86X58 Q93008	A0A087WVF5 A0A0A0MRC4 A0A0A0MSK4 Q86YR5
PDB IDs		5VBD 5WCH
Enriched GO Terms of Interacting Partners?
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