PABPN1 and CARM1

Number of citations of the paper that reports this interaction (PubMedID 11850402)
83

Data Source:
BioGRID (enzymatic study)

		PABPN1	CARM1
Description		poly(A) binding protein nuclear 1	coactivator associated arginine methyltransferase 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Nuclear Inclusion Body Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm Cytosol RNA Polymerase II Transcription Factor Complex
	Molecular Function	RNA Binding Protein Binding RNA Polymerase Binding	Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein Methyltransferase Activity Histone-arginine N-methyltransferase Activity Protein-arginine N-methyltransferase Activity Nuclear Receptor Transcription Coactivator Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity (H3-R17 Specific) Histone Methyltransferase Activity Protein Homodimerization Activity Transcription Regulatory Region DNA Binding Lysine-acetylated Histone Binding
	Biological Process	MAPK Cascade MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription RNA Processing Muscle Contraction Poly(A)+ MRNA Export From Nucleus MRNA 3'-end Processing Modification By Virus Of Host MRNA Processing Cellular Response To Lipopolysaccharide Positive Regulation Of Polynucleotide Adenylyltransferase Activity	Regulation Of Growth Plate Cartilage Chondrocyte Proliferation Regulation Of Transcription, DNA-templated DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Aging Positive Regulation Of Cell Proliferation Viral Process Histone Methylation Regulation Of Lipid Metabolic Process Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Protein Binding Regulation Of Intracellular Estrogen Receptor Signaling Pathway Histone H3-R2 Methylation Histone H3-R17 Methylation Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of NF-kappaB Transcription Factor Activity Response To CAMP Endochondral Bone Morphogenesis Protein Localization To Chromatin Regulation Of MRNA Binding Negative Regulation Of Dendrite Development
Pathways		Inhibition of Host mRNA Processing and RNA Silencing mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	RORA activates gene expression BMAL1:CLOCK,NPAS2 activates circadian gene expression PPARA activates gene expression PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Activation of gene expression by SREBF (SREBP) RMTs methylate histone arginines Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by PPARalpha Circadian Clock TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest Estrogen-dependent gene expression
Drugs
Diseases		Oculopharyngeal muscular dystrophy (OPMD)
GWAS		Body mass index ( 26865924)	C-reactive protein levels or LDL-cholesterol levels (pleiotropy) ( 27286809) C-reactive protein levels or total cholesterol levels (pleiotropy) ( 27286809) Psoriasis ( 25574825 23143594) Psoriasis vulgaris ( 26626624)
Interacting Genes		13 interacting genes: CARM1 DNAJB4 HNRNPA1 HSP90AA1 IL7R LATS1 LINC00839 PRMT3 SMARCA4 SNW1 STAU1 TNPO1 YWHAQ	32 interacting genes: AXIN1 CREBBP CTNNB1 DAXX DNAJA3 DZIP3 ELAVL1 EP300 FLII FOS GRIP1 H3-3A H3-3B H3C1 MALT1 MEF2D MYOD1 MYOG NCOA1 NCOA2 NUDT21 PABPC1 PABPN1 PYGO1 QKI RABGAP1 RELA SMARCA4 SPAG8 SRCAP TP53 UBE2I
Entrez ID		8106	10498
HPRD ID		03787	09158
Ensembl ID		ENSG00000100836	ENSG00000142453
Uniprot IDs		Q86U42	Q86X55
PDB IDs		3B4D 3B4M 3UCG	2Y1W 2Y1X 4IKP 5DWQ 5DX0 5DX1 5DX8 5DXA 5DXJ 5U4X 6ARJ 6ARV 6D2L 6DVR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?