GRPEL1 and SFTPB

		GRPEL1	SFTPB
Description		GrpE like 1, mitochondrial	surfactant protein B
Image		No pdb structure
GO Annotations	Cellular Component	PAM Complex, Tim23 Associated Import Motor Nucleoplasm Mitochondrion Mitochondrial Matrix	Extracellular Region Extracellular Space Nucleoplasm Lysosome Multivesicular Body Endoplasmic Reticulum Membrane Lamellar Body Clathrin-coated Endocytic Vesicle Alveolar Lamellar Body Multivesicular Body Lumen
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Protein Binding Protein Homodimerization Activity Unfolded Protein Binding Chaperone Binding
	Biological Process	Protein Folding Protein Import Into Mitochondrial Matrix Regulation Of Catalytic Activity	Sphingolipid Metabolic Process Respiratory Gaseous Exchange Animal Organ Morphogenesis Cellular Protein Metabolic Process
Pathways		Mitochondrial protein import	Surfactant metabolism Defective pro-SFTPB causes pulmonary surfactant metabolism dysfunction 1 (SMDP1) and respiratory distress syndrome (RDS) Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5) Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4)
Drugs
Diseases			Pulmonary surfactant metabolism dysfunction (SMDP)
GWAS			Blood protein levels ( 30072576)
Interacting Genes		8 interacting genes: DSP FAM184B FGFBP2 MED28 NKX3-2 SFTPB WBP2 XYLB	2 interacting genes: CTSH GRPEL1
Entrez ID		80273	6439
HPRD ID		07550	01523
Ensembl ID		ENSG00000109519	ENSG00000168878
Uniprot IDs		Q9HAV7	D6W5L6 P07988
PDB IDs			1DFW 1KMR 1RG3 1RG4 1SSZ 2DWF 2JOU 2M0H 2M1T
Enriched GO Terms of Interacting Partners?
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