EFHC2 and EDC3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		EFHC2	EDC3
Description		EF-hand domain containing 2	enhancer of mRNA decapping 3
Image
GO Annotations	Cellular Component	Microtubule	P-body Cytosol Membrane Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Calcium Ion Binding Protein Binding	MRNA Binding Protein Binding Identical Protein Binding Phosphodiesterase Decapping Endonuclease Activity
	Biological Process	Regulation Of Neuron Projection Development Cellular Response To Leukemia Inhibitory Factor	Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Cytoplasmic MRNA Processing Body Assembly Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways			mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS		Mean arterial pressure ( 29403010)	Caffeine consumption ( 21490707) Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level) ( 27702941) Caffeine metabolism (plasma 1,3-dimethylxanthine (theophylline) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Craniofacial microsomia ( 26853712)
Interacting Genes		37 interacting genes: ARHGEF5 ARMC7 CACNB4 CCDC120 CCHCR1 CCNG2 CDKN2A CLIC3 COPE CYFIP1 DGCR6 EDC3 EFHC1 EGLN3 EMD EXOC8 FAM107A HNRNPLL JAKMIP2 KIF9 LONRF1 MAPK9 NCDN NCK2 NDOR1 NR3C1 PBLD PLOD3 PTK6 RAD51D RUNX1T1 SNRNP25 SPG21 STK16 TRIM42 TSSK3 TUBGCP4	9 interacting genes: ANXA10 DCP1A DCP1B DDX6 EFHC2 REEP5 YWHAB YWHAG ZFP36
Entrez ID		80258	80153
HPRD ID		06540	07954
Ensembl ID		ENSG00000183690	ENSG00000179151
Uniprot IDs		Q5JST6	Q96F86
PDB IDs		2Z13 2Z14	2VC8 2WAX 2WAY 3D3J 3D3K 6S8S
Enriched GO Terms of Interacting Partners?
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