TNIP3 and TAX1BP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TNIP3	TAX1BP1
Description		TNFAIP3 interacting protein 3	Tax1 binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Polyubiquitin Modification-dependent Protein Binding	Protein Binding Kinase Binding Metal Ion Binding
	Biological Process	MyD88-independent Toll-like Receptor Signaling Pathway Inflammatory Response Protein Deubiquitination Toll-like Receptor 4 Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Lipopolysaccharide	Apoptotic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process
Pathways		Ovarian tumor domain proteases	Regulation of TNFR1 signaling Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Breast cancer ( 23468962) Multiple sclerosis ( 31604244)	Adventurousness ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Asthma (childhood onset) ( 31036433) Hypospadias ( 25108383) Metabolite levels ( 23823483)
Interacting Genes		11 interacting genes: DAZAP2 KRT40 KRTAP10-3 KRTAP10-8 LZTS2 NOTCH2NLA TAX1BP1 TNFAIP3 TNIP1 UBC ZBTB8A	40 interacting genes: ARHGAP1 AZI2 COG7 CWF19L2 CXXC1 DAZAP2 DSTN FAM168A FAM189A2 FOXC2 GABARAP GABARAPL1 GABARAPL2 IKBKG KIF5B LGALS8 LMO3 MAP1LC3B MAP1LC3C MRPL11 MRPL53 NMRK1 ORC5 PLEKHN1 RAB18 RAD18 RAD54L2 RIPK1 RNF11 SSX2 STARD13 TBC1D17 TCEA2 TNFAIP3 TNIP3 TRAF6 TRIM14 TSG101 TSHZ3 UBC
Entrez ID		79931	8887
HPRD ID		16268	05618
Ensembl ID		ENSG00000050730	ENSG00000106052
Uniprot IDs		Q96KP6	B4DSG5 Q86VP1
PDB IDs			2M7Q 4BMJ 4NLH 4Z4K 4Z4M 5AAS 5YT6 5Z7G
Enriched GO Terms of Interacting Partners?
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