TUSC3 and BMI1

Number of citations of the paper that reports this interaction (PubMedID 19451220)
34

Data Source:
BioGRID (pull down)

		TUSC3	BMI1
Description		tumor suppressor candidate 3	BMI1 proto-oncogene, polycomb ring finger
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GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Oligosaccharyltransferase Complex	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytosol Nuclear Body PcG Protein Complex PRC1 Complex
	Molecular Function	Magnesium Ion Transmembrane Transporter Activity	Protein Binding Zinc Ion Binding RING-like Zinc Finger Domain Binding Promoter-specific Chromatin Binding
	Biological Process	Protein N-linked Glycosylation Magnesium Ion Transport Protein N-linked Glycosylation Via Asparagine Cognition Transmembrane Transport Magnesium Ion Transmembrane Transport	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Silencing Segment Specification Regulation Of Gene Expression Hemopoiesis Histone H2A-K119 Monoubiquitination Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Fibroblast Proliferation Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of G0 To G1 Transition
Pathways		Asparagine N-linked glycosylation Miscellaneous transport and binding events	Oxidative Stress Induced Senescence SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription Transcriptional Regulation by E2F6
Drugs
Diseases		Nonsyndromic autosomal recessive mental retardation (NS-ARMR)	Penile cancer
GWAS		Intelligence ( 22449649) Metabolite levels ( 23823483) Methamphetamine dependence ( 23594818) Prudent dietary pattern ( 28644415) Pulmonary function decline ( 22424883) Response to cytadine analogues (cytosine arabinoside) ( 24483146) Response to SSRI in MDD or openness ( 29559929)	Prostate-specific antigen levels ( 28139693)
Interacting Genes		2 interacting genes: BMI1 PPP1CA	37 interacting genes: CBX8 CEP126 CSNK2B E2F6 FOXS1 H2AC18 H2AC20 H2AC4 H2AX H3-4 IMMT KAT5 KMT2A LRIF1 MAPK14 MLLT1 MUC1 NDEL1 PCGF3 PCGF6 PGR PHC1 PHC2 PTN RING1 RNF114 RNF2 RRM1 SOCS2 TRIM27 TUSC3 UBE2D2 UBE2D3 UBE2I USP11 VPS11 ZBTB16
Entrez ID		7991	648
HPRD ID		03228	01277
Ensembl ID		ENSG00000104723	ENSG00000168283
Uniprot IDs		Q13454	P35226
PDB IDs		4M8G 4M90 4M91 4M92	2H0D 2NA1 3RPG 4R8P 5FR6
Enriched GO Terms of Interacting Partners?
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