HDAC11 and MRPS25

		HDAC11	MRPS25
Description		histone deacetylase 11	mitochondrial ribosomal protein S25
Image		No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleus Plasma Membrane	Mitochondrion Mitochondrial Inner Membrane Ribosome
	Molecular Function	Histone Deacetylase Activity Protein Binding Transcription Factor Binding NAD-dependent Histone Deacetylase Activity (H3-K14 Specific)	Structural Constituent Of Ribosome
	Biological Process	Chromatin Organization Oligodendrocyte Development Histone Deacetylation Histone H3 Deacetylation	Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		NOTCH1 Intracellular Domain Regulates Transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Notch-HLH transcription pathway	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs		Belinostat Panobinostat
Diseases
GWAS		Body mass index ( 26426971) Height ( 20881960) Hip circumference adjusted for BMI ( 25673412) Ulcerative colitis ( 26278503)
Interacting Genes		8 interacting genes: CDC25A CDKN1A HDAC6 MAPK6 MRPS25 NELFCD NUP210 PHYHIP	7 interacting genes: CAND2 COLQ FBLN2 HDAC11 MKRN2 NUAK1 XPC
Entrez ID		79885	64432
HPRD ID		09146	17594
Ensembl ID		ENSG00000163517	ENSG00000131368
Uniprot IDs		B5MCQ6 E7ETT9 Q6IA14 Q96DB2	P82663
PDB IDs			3J9M 6NU2 6NU3
Enriched GO Terms of Interacting Partners?
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