HPS6 and TTC19

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		HPS6	TTC19
Description		HPS6 biogenesis of lysosomal organelles complex 2 subunit 3	tetratricopeptide repeat domain 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endoplasmic Reticulum Membrane BLOC-2 Complex Early Endosome Membrane	Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody Respiratory Chain
	Molecular Function	Protein Binding Rab GTPase Binding GTP-dependent Protein Binding	Protein Binding
	Biological Process	Organelle Organization Blood Coagulation Melanocyte Differentiation Lysosome Localization Protein Localization To Membrane	Mitotic Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly Oxidation-reduction Process
Pathways
Drugs
Diseases		Hermansky-Pudlak syndrome (HPS)	Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435)
Interacting Genes		9 interacting genes: CREB1 EP300 HPS5 MARK4 MNAT1 OSGEP PIK3CB PUM3 TTC19	12 interacting genes: ATXN1 CCDC33 CHMP4A EIF4ENIF1 HPS6 IHO1 L3MBTL3 NAB2 REL SPRED1 UBA1 UPF3B
Entrez ID		79803	54902
HPRD ID		08471	07899
Ensembl ID		ENSG00000166189	ENSG00000011295
Uniprot IDs		Q86YV9	A0A024RD83 Q6DKK2
PDB IDs
Enriched GO Terms of Interacting Partners?
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