ACSS3 and LEFTY2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ACSS3	LEFTY2
Description		acyl-CoA synthetase short chain family member 3	left-right determination factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Matrix	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Collagen-containing Extracellular Matrix
	Molecular Function	Acetate-CoA Ligase Activity ATP Binding Butyrate-CoA Ligase Activity Propionate-CoA Ligase Activity	Cytokine Activity Transforming Growth Factor Beta Receptor Binding Growth Factor Activity
	Biological Process	Ketone Body Biosynthetic Process	Platelet Degranulation Transforming Growth Factor Beta Receptor Signaling Pathway Multicellular Organism Development Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation BMP Signaling Pathway SMAD Protein Signal Transduction
Pathways		Synthesis of Ketone Bodies	Platelet degranulation Signaling by NODAL Regulation of signaling by NODAL
Drugs
Diseases
GWAS		Age-related cataracts (age at onset) ( 25352737) Alcohol consumption ( 31358974) Bitter alcoholic beverage consumption ( 31046077) Lateral orbital frontal cortex volume ( 31530798) Medial orbital frontal cortex volume ( 31530798) Pars orbitalis volume ( 31530798) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457) Prudent dietary pattern ( 28644415) Response to antidepressant treatment (citalopram) ( 23726668)
Interacting Genes		1 interacting genes: LEFTY2	2 interacting genes: ACSS3 MAPK8IP2
Entrez ID		79611	7044
HPRD ID		13385	03526
Ensembl ID		ENSG00000111058	ENSG00000143768
Uniprot IDs		A0A0B4J1R2 Q9H6R3	A1NY82 O00292
PDB IDs
Enriched GO Terms of Interacting Partners?
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